Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Third Edition (häftad)
Häftad (Paperback)
Antal sidor
McGraw-Hill Education / Medical
Hyman, Steven / Malenka, Robert
255 x 175 x 15 mm
808 g
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Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Third Edition (häftad)

Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Third Edition

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Häftad Engelska, 2015-02-16
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Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others.

the neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. in the final section, the authors use the concepts presented in the first two sections to explainhow irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations.


  • NEW chapter on neuroinflammation
  • All chemical structure illustrations have been redrawn and improved
  • Fully updated to reflect the latest breakthroughs and new drugs
  • The most well-written and easily understood work on the subject
  • More than 300 full-color illustrations!
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Passar bra ihop

  1. Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Third Edition
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Övrig information

Eric J. Nestler, MD is Professor and Chairman of the Department of Psychiatry and the Center for Basic Neuroscience at the Southwestern Medical School, Graduate School of Biomedical Sciences, Dallas Texas. He is also the Lou and Ellen McGinley Distinguished Chair in Psychiatric Research. The goal of Dr. Nestler's research is to better understand the ways in which the brain responds to repeated perturbations under normal and pathological conditions. A major focus of the research is drug addiction: to identify molecular changes that drugs of abuse produce in the brain to cause addiction, and to characterize the genetic and environmental factors that determine individual differences in the ability of the drugs to produce these changes. A related interest is to understand the contribution of the brain's reward regions to the regulation of normal mood as well as the abnormalities in mood and motivation seen in depression. Dr. Nestler has authored or edited 5 books, and has authored or co-authored 180 original research articles and 90 review articles and book chapters. He currently mentors seven post-doctoral fellows and six graduate students. He has trained 27 post-doctoral researchers, eight research track residents, and ten graduate students. Dr. Nestler is the recipient of numerous awards and honors, including the Pfizer Scholars Award (1987), Sloan Research Fellowship (1987), McKnight Scholar Award (1989), Efron Award of the American College of Neuropsychopharmacology (1994), and Pasarow Foundation Award for Neuropsychiatric Research (1998). He has served on the Board of Scientific Counselors of the National Institute on Drug Abuse, and currently serves on the Scientific Advisory Boards of the National Alliance for Research in Schizophrenia and Depression and of the National Alliance for Autism Research. Dr. Nestler is also a member of the National Advisory Mental Health Council, the Council of the Society for Neuroscience, and the Council of the American College of Neuropsychopharmacology

Steven E. Hyman, MD is Provost of Harvard University and Professor of Neurobiology at Harvard Medical School, Boston, MA. From 1996 to 2001, he served as Director of the National Institute of Mental Health (NIMH), the component of the US National Institutes of Health charged with generating the knowledge needed to understand and treat mental illness. Before serving as Director of NIMH, Dr. Hyman was Professor of Psychiatry at Harvard Medical School, Director of Psychiatry Research at Massachusetts General Hospital , and the first faculty Director of Harvard University's Mind, Brain, and Behavior Initiative. In the laboratory he studied the molecular biology of neurotransmitter action. Dr. Hyman is a member of the Institute of Medicine of the National Academy of Sciences and of the American Academy of Arts and Sciences. He is currently serves as Editor of the Annual Review of Neuroscience. He received his BA from Yale College in 1974 summa cum laude, and...


1. Fundamentals of Neuropharmacology

1. Basic Principles of Neuropharmacology

2. Cellular Basis of Communication

3. Synaptic Transmission

4. Signal Transcuction in the Brain

2. Neural Substrates of Drug Action

5. Excitatory and Inhibitory Amino Acids

6. Monoamines, Acetylcholine, and Orexin

7. Neuropeptides

8. Atypical Neurotransmitters

Neuropharmacology of Neural Systems and Disorders

9. Autonomic Nervous System

10. Neural and Neuroendocrine Control of Internal Mileau

11. Pain

12. Neuroinflammation

13. Sleep and Arousal

14. Cognitive Function and Behavior

15. Mood and Emotion

16. Reinforcement and Addiction

17. Schizophrenia and Other Psychoses

18. Neurodegeneration

19. Seizures

20. Stroke and Migraine