Presynaptic Inhibition and Neural Control

"...this scholarly and rigorous treatise of presynaptic inhibition will prove valuable to anyone exploring the depths of synaptic integration."--The Quarterly Review of Biology "Overall, this book is well-written and nicely produced. The list of authors is impressive and certainly represents leaders in the field. The editors have also done a good job in achieving a relatively uniform style among the different chapters and the cross-references between the different chapters are quite helpful." - Dr. Robert Chen, The Canadian Journal of Neurological Sciences

Introduction; Part I: Basic Mechanisms of Presynaptic Control; 1. Anatomical Basis for Presynaptic Inhibition on Primary Sensory Fibers; 2. Chloride Transport, Osmotic Balance and Presynaptic Inhibition; 3. Mechanisms and Physiological Implications of Receptor-Mediated Inhibition of Voltage-Dependent Ca2+ Channels; 4. Presynaptic Inhibition and Faciliation of Transmitter Release; 5. Primary Afferent Depolarization and Presynaptic Inhibition; 6. Control of Action Potential Invasion into Terminal Arborizations; 7. Action Potential Propagation Along Primary Afferents and Presynaptic Inhibition in Clarkes's Column of the Spinal Cord; 8. Two Types of Inhibition in the Spinal Cord; 9. The Relative Contributions of GABAA and GABB Receptors to Presynaptic Inhibition of Group Ia EPSPs; 10. Modulation of Transmitter Release From Ia Afferents by Their Preceding Activity - A 'Post-activation Depression'; 11. Presynaptic Inhibition of Neuromuscular Transmission in Crayfish; 12. Regulation of Primary Eighth Nerve Synapses on the Mauthner Cell; 13. Some Unanswered Questions About the Mechanisms and Function of Presynaptic Inhibition; Part II: Presynaptic Control of Segmental Inputs; 14. Presynaptic Inhibition and the Anatomy of Group Ia Afferents; 15. Ia Fiber Architecture: Implications for the Functional Role of Presynaptic Inhibition; 16. Dynamic Aspects of Presynaptic Function in the Developing Mammalian Spinal Cord; 17. Selectivity of the Presynaptic Control of Synaptic Effectiveness of Group 1 Afferents in the Mammalian Spinal Cord; 18. Presynaptic Inhibition Can Act as a Filter of Input from Tendon Organs during Muscle Contraction; 19. Neuronal Systems Involved in Modulation Synaptic Transmission from Group II Muscle Afferents; 20. Presynaptic Inhibition of Synaptic Transmssion from Sensory, Intemeuronal and Supraspinal Neurons to Spinal Target Cells in Lamprey; 21. Differential Control of Presynaptic Inhibition of Ia Terminals during Voluntary Movement in Humans; 22. PAD and Modulation of Evoked Group II Flexion Reflexes during MLR-Evoked Fictive Locomotion; 23. Presynaptic Mechanisms during Locomotion; 24. Modulation of Excitatory Perineal Reflexes and Sacral Striated Motoneuron during Micturition in the Cat; 25. A Contribution of Dorsal Root Reflexes to Peripheral Inflammation; 26. Modulation of Nociceptive Information at the Presynaptic Terminals of Primary Afferent Fibers; Bibliography; Index