- Format
- Häftad (Paperback)
- Språk
- Engelska
- Antal sidor
- 400
- Utgivningsdatum
- 2011-03-31
- Upplaga
- 3
- Förlag
- Pearson
- Illustratör/Fotograf
- Illustrations
- Illustrationer
- Illustrations
- Dimensioner
- 235 x 157 x 20 mm
- Vikt
- Antal komponenter
- 1
- ISBN
- 9780273730682
- 590 g
Understanding Immunology
Cell and Molecular Biology in Action
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Recensioner i media
"Nice book size, clear helpful diagrams and reasonable sized chapters, useful glossary. Helpful revision and updates in a fast changing field" - Peter Bentley, Head of Biology Department, City University
"A very accessible text for students. The diagrams are clear and there are good Q&A sections" - Anne Humphreys, Senior Lecturer in Microbiology, Faculty of Science, Liverpool John Moores University
Övrig information
Dr. Peter Wood is a Lecturer in the Faculty of Life Sciences at the University of Manchester. He has over 20 years of teaching experience, both in the UK and in the USA, and is widely published in the literature. His current research interest is the role of cytokines in the development of diabetes.
Innehållsförteckning
Contents
Preface
Acknowledgements
1 The threat to the body: the role and requirements of the immune system
1.1 The role and complexity of the immune system
1.2 Pathogens differ in size, lifestyle and how they cause disease
1.3 How do pathogens cause disease and what protection is there?
1.4 Conclusion
1.5 Summary
1.6 Questions and answers
1.7 Further reading
2 The immediate response to infection: innate immunity and the
inflammatory response
2.1 The response to infection
2.2 The immediate response to infection the innate immune system
2.3 Cytokines hormones of the immune system
2.4 The inflammatory response and cell migration
2.5 Cell migration through blood and into tissue
2.6 The inflammatory response
2.7 Systematic inflammation involvement of the brain and liver
2.8 Opsonins cans
2.9 Interferons and natural killer cells
2.10 The innate immune response limits the early replication of pathogens
2.11 Summary
2.12 Questions and answers
2.13 Further reading
3 Specific immune recognition: B lymphocytes and the antibody molecule
3.1 Introduction to the specific immune system
3.2 Antibody structure
3.3 Recognition by antibody antigens and epitopes
3.4 There are different antibody classes with different biological functions
3.5 Antibody can be secreted or expressed on the cell surface of B lymphocytes
3.6 Summary
3.7 Questions and answers
3.8 Further reading
4 T lymphocytes and MHC-associated recognition of antigen
4.1 There are different types of T lymphocytes
4.2 T cells recognise antigen through their T cell receptor (TCR)
4.3 The major histocompatibility complex
4.4 Recognition of antigen by T cells
4.5 Antigens must be processed before they can be presented by MHC molecules
4.6 Summary ;
4.7 Questions and answers
4.8 Further reading
5 Lymphocyte development and the generation of antigen receptors
5.1 The production of lymphocytes: lymphopoiesis
5.2 B lymphocytes are produced in the bone marrow
5.3 T lymphocytes finish their production in the thymus
5.4 During their development lymphocytes must generate huge numbers of Ig and TCR receptors with different antigen specificities
5.5 Developing lymphocytes rearrange their lg or TCR genes in a carefully controlled order
5.6 Why is there continuous production of lymphocytes, most of which die?
5....