DNA Methylation Microarrays (häftad)
Fler böcker inom
Format
Häftad (Paperback / softback)
Språk
Engelska
Antal sidor
256
Utgivningsdatum
2019-10-21
Förlag
Chapman & Hall/CRC
Dimensioner
234 x 155 x 15 mm
Vikt
386 g
Antal komponenter
1
ISBN
9780367387402

DNA Methylation Microarrays

Experimental Design and Statistical Analysis

av Sun-Chong Wang, Art Petronis
Häftad,  Engelska, 2019-10-21
902
Köp
Spara som favorit
  • Skickas från oss inom 10-15 vardagar.
  • Fri frakt över 249 kr för privatkunder i Sverige.
Finns även som
Visa alla 2 format & utgåvor
Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays, many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-chip) studies. After introducing basic statistics, the book describes wet-bench technologies that produce the data for analysis and explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections. It then explores differential methylation and genomic tiling arrays. Focusing on exploratory data analysis, the next several chapters show how cluster and network analyses can link the functions and roles of unannotated DNA elements with known ones. The book concludes by surveying the open source software (R and Bioconductor), public databases, and other online resources available for microarray research. Requiring only limited knowledge of statistics and programming, this book helps readers gain a solid understanding of the methodological foundations of DNA microarray analysis.
Visa hela texten

Passar bra ihop

  1. DNA Methylation Microarrays
  2. +
  3. The Anxious Generation

De som köpt den här boken har ofta också köpt The Anxious Generation av Jonathan Haidt (inbunden).

Köp båda 2 för 1191 kr

Kundrecensioner

Har du läst boken? Sätt ditt betyg »

Fler böcker av författarna

Övrig information

Wang, Sun-Chong; Petronis, Art

Innehållsförteckning

Preface. Applied Statistics. DNA Methylation Microarrays and Quality Control. Experimental Design. Data Normalization. Significant Differential Methylation. High-Density Genomic Tiling Arrays. Cluster Analysis. Statistical Classification. Interdependency Network of DNA Methylation. Time Series Experiment. Online Annotations. Public Microarray Data Repositories. Open Source Software for Microarray Data Analysis. References. Index.

Du kanske gillar