Amyotrophic Lateral Sclerosis (häftad)
Format
Häftad (Paperback / softback)
Språk
Engelska
Antal sidor
864
Utgivningsdatum
2019-10-17
Förlag
CRC Press
Antal komponenter
1
ISBN
9780367391843
Amyotrophic Lateral Sclerosis (häftad)

Amyotrophic Lateral Sclerosis

Häftad Engelska, 2019-10-17
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With cutting-edge contributions from internationally recognized experts and field pioneers, Amyotrophic Lateral Sclerosis is the definitive guide to the subject. Formatted in an easily accessible manner, with summaries of key points at the end of each chapter, this guide covers all the essential information clinicians require for daily practice, as well as providing a reader-friendly approach to every aspect of ALS with detailed sections on the clinical features of disease, translational research, patient care and management, and emerging therapies.
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Övrig information

Hiroshi Mitsumoto, Serge Przedborski, Paul H. Gordon

Innehållsförteckning

Overview of Clinical ALS. History. Epidemiology. Pathology. Clinical Features: Motor System. Clinical Features: Dementia and Cognitive Deficits. Familial ALS and Genetic Approaches to ALS. Electrophysiology and Other Objective Markers. Classification, Diagnosis and Presentation of Diagnosis of ALS. Natural History. Translational Research in ALS: Mechanisms behind therapy. Motor Neuron: The origin, definition and function. Neurodegeneration. Excitotoxicity. Oxidative Stress. Neuroinflammation. Apoptosis. Cytoskeleton. Mitochondria. Environmental Neurotoxicity. Genetic Causes and Predisposition. Protein Aggregate Disease. Proteiomic and Metabolomic Approach. Infections and Autoimmunity. Gene Transfer Technology. High Through-put Technology. Animal Models. Restoration-Practical Approach. Clinical Trial Methodology. ALS Therapy: Care and Management. Multidisciplinary Approach: Ideal Care Centers and World Perspective. Impact of National ALS Care Database and Practice Parameters. Symptomatic Pharmacotherapy: Bulbar and Constitutional Symptoms. Pharmacotherapy: In clinical trials. Physical Rehabilitation. Speech Therapy and Augmentative Communication/Assistive Technology. Nutritional treatment: Theoretical and Practical issues. Respiratory care: Basic and Practical. Psychosocial care: Patient and Caregiver Support. Palliative Care. Palliative Care: Family Perspective. Decision Making for End of Life. National ALS Study Group: Future of ALS Clinical Research