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Köp båda 2 för 2036 krThis book consists of 17 chapters on a variety of topics related to drug design and action. This book is intended as a possible text for undergraduate chemistry students interested in medicinal chemistry, or for graduate students as a means to learn the basics of medicinal chemistry. classical approaches are described for drug design with the inclusion of the more recent context of the human genome project In summary, some medicinal chemists in academia or the pharmaceutical industry may find this book instructive for certain classes of biomolecules or classical approaches to drug design. It should probably be included in most comprehensive library collections of medicinal chemistry texts and monographs. Bruce L. Currie, Department of Pharmaceutical Sciences, Loma Linda University, California, in Journal of Medicinal Chemistry, , Vol. 50, No. 1, 2007 The fourth edition of this book includes the latest information on topics such as gene therapy, computer-aided design, and molecular techniques including proteomics. real-world examples that illustrate the principles of drug design New features of this edition include: coverage of agonists and antagonists of neurotransmitters; the design of stable peptide-like drugs; the human genome and its impact on drug discovery and development; advances in therapy and pharmacokinetics. In Anticancer Research, Vol. 26, 2006 Promo Copy
H. John Smith, Hywel Williams
Processes of Drug Handling by the Body. The Design of Drug Delivery Systems. Fundamental Pharmacokinetics. Intermolecular Forces and Molecular Modeling. Drug Chirality and its Pharmacological Consequences. Quantitative StructureActivity Relationships (QSAR) in Drug Design. Prodrugs. From Program Sanction to Clinical Trials: A Partial View of the Quest for Arimidex, A Potent, Selective Inhibitor of Aromatase. Design of Enzyme Inhibitors as Drugs. Peptide Drug Design. Combinatorial Chemistry: A Tool for Drug Discovery. Recombinant DNA Technology: Monoclonal Antibodies. The Human Genome and its Impact on Drug Discovery and Therapy. The Chemotherapy of Cancer. Neurotransmitters, Agonists, and Antagonists. Design of Antibacterial, Antifungal, and Antiviral Agents. Pharmaceutical Applications of Bioinorganic Chemistry. Index.