Biomechatronic Design in Biotechnology (inbunden)
Format
Inbunden (Hardback)
Språk
Engelska
Antal sidor
304
Utgivningsdatum
2011-07-14
Upplaga
1
Förlag
John Wiley & Sons Inc
Illustrationer
Illustrations
Dimensioner
241 x 160 x 19 mm
Vikt
589 g
Antal komponenter
1
Komponenter
,
ISBN
9780470573341
Biomechatronic Design in Biotechnology (inbunden)

Biomechatronic Design in Biotechnology

A Methodology for Development of Biotechnological Products

Inbunden Engelska, 2011-07-14
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a must-read for all modern bio-scientists and engineers working in the field of biotechnology. Biotechnology Journal, 2012, 7 A cutting-edge guide on the fundamentals, theory, and applications of biomechatronic design principles Biomechatronic Design in Biotechnology presents a complete methodology of biomechatronics, an emerging variant of the mechatronics field that marries biology, electronics, and mechanics to create products where biological and biochemical, technical, human, management-and-goal, and information systems are combined and integrated in order to solve a mission that fulfills a human need. A biomechatronic product includes a biological, mechanical, and electronic part. Beginning with an overview of the fundamentals and theory behind biomechatronic technology, this book describes how general engineering design science theory can be applied when designing a technical system where biological species or components are integrated. Some research methods explored include schemes and matrices for analyzing the functionality of the designed products, ranking methods for screening and scoring the best design solutions, and structuring graphical tools for a thorough investigation of the subsystems and sub-functions of products. This insightful guide also: * Discusses tools for creating shorter development times, thereby reducing the need for prototype testing and verification * Presents case study-like examples of the technology used such as a surface plasmon resonance sensor and a robotic cell culturing system for human embryonic stem cells * Provides an interdisciplinary and unifying approach of the many fields of engineering and biotechnology used in biomechatronic design By combining designs between traditional electronic and mechanical subsystems and biological systems, this book demonstrates how biotechnology and bioengineering design can utilize and benefit from commonly used design tools and benefit humanity itself.
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a must-read for all modern bio-scientists and engineers working in the field of biotechnology. (Biotechnology Journal July 2012)

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Övrig information

Professor Carl-Fredrik Mandenius is head of the Division of Biotechnology at Linkoping University in Sweden. His main research interests include biochemical and bio-production engineering, bioprocess monitoring and control, stem cell technology, and biosensor technology. He was a director for process R&D at Pharmacia AB and has coordinated several EU networks on hESC-derived models for drug testing. Professor Mats Bjorkman is head of the Division of Assembly Technology at Linkoping University in Sweden. His main research interests include design and operation of flexible manufacturing systems and equipment. He has also been involved in research that has developed from traditional mechanical industries to include areas such as electronic manufacturing and manufacturing of biotech equipment, as well as pharmaceutical products.

Innehållsförteckning

PREFACE xiii 1 Introduction 1 1.1 Scope of Design / 1 1.2 Definition of Biomechatronic Products / 3 1.3 Principles of Biomechatronics / 4 1.4 Brief History of the Development of Biomechatronic Products and Engineering / 7 1.5 Aim of This Book / 9 References / 10 PART I FUNDAMENTALS 13 2 Conceptual Design Theory 15 2.1 Systematic Design / 15 2.1.1 Design for Products / 15 2.1.2 Origin of the Design Task / 18 2.1.3 Development of Design Thinking / 18 2.1.4 Recent Methods / 20 2.2 Basics of Technical Systems / 21 2.2.1 Energy, Material, and Signals and Their Conversion / 22 2.2.2 Interrelationships of Functions / 22 2.2.3 Interrelationship of Constructions / 25 2.2.4 Interrelationship of Systems / 25 2.3 Psychology in the Systematic Approach / 25 2.4 A General Working Methodology / 26 2.4.1 Analysis for Resolving Technical Problems / 27 2.4.2 Abstraction of Interrelationships of Systems / 28 2.4.3 Synthesis of the Technical System / 28 2.5 Conceptual Design / 28 2.6 Abstraction inOrder to Identify Essential Problems / 29 2.7 Developing the Concepts / 31 2.7.1 Organizing the Development Process / 33 2.8 Concluding Remarks / 34 References / 35 3 Biotechnology and Mechatronic Design 37 3.1 Transduction of the Biological Science into Biotechnology / 37 3.2 Biological Sciences and Their Applications / 39 3.3 Biotechnology and Bioengineering / 42 3.4 Applying Mechatronic Theory to Biotechnology: Biomechatronics / 44 3.5 Conclusions / 47 References / 48 4 Methodology for Utilization of Mechatronic Design Tools 49 4.1 Idea of Applying the Mechatronic Design Tools / 49 4.2 Table of User Needs / 51 4.3 List of Target Specifications / 52 4.4 Concept Generation Chart / 52 4.4.1 Basic Concept Component Chart / 53 4.4.2 Permutation Chart / 54 4.5 Concept Screening Matrix / 55 4.6 Concept Scoring Matrix / 56 4.7 Hubka Eder Mapping / 57 4.7.1 Overview Hubka Eder Map / 57 4.7.2 Zoom-in Hubka Eder Mapping / 59 4.8 Functions Interaction Matrix / 60 4.8.1 Functions Interaction Matrix for Systems and Subsystems / 60 4.8.2 Functions Interaction Matrix for Systems and Transformation Process / 61 4.8.3 Design Structure Matrix / 61 4.9 Anatomical Blueprint / 62 4.10 Conclusions / 63 References / 63 PART II APPLICATIONS 65 5 Blood Glucose Sensors 67 5.1 Background of Blood Glucose Analysis / 67 5.2 Specification of Needs for Blood Glucose Analysis / 70 5.3 Design of Blood Glucose Sensors / 71 5.3.1 Generation of Sensor Concepts / 71 5.4 Description of the Systems Involved in the Design Concepts for Glucose Blood Sensors / 76 5.4.1 Biological Systems / 77 5.4.2 Technical Systems / 77 5.4.3 Information Systems / 78 5.4.4 Management and Goal Systems / 78 5.4.5 Human Systems / 79 5.4.6 Active Environment / 79 5.4.7 Interactions Between the Systems and Functions of the Design / 79 5.4.8 Anatomical Blueprints from the Functions Interaction Matrix Analysis / 81 5.5 Conclusions / 82 References / 82 6 Surface Plasmon Resonance Biosensor Devices 85 6.1 Introduction / 85 6.2 Design Requirements on SPR Systems / 88 6.2.1 Needs and Specifications of an SPR Design / 88 6.3 Mechatronic Design Approach of SPR Systems / 89 6.3.1 Generation of Design Alternatives / 89 6.3.2 Hubka Eder Mapping of the Design Alternatives / 92 6.4 Detailed Design of Critical SPR Subsystems / 99 6.4.1 Design of the Sensor Surface / 100 6.4.2 Design of the Fluidic System / 103 6.5 Conclusions / 109 References / 109 7 A Diagnostic Device for Helicobacter pylori Infection 113 7.1 Diagnostic Principle of Helicobacter Infection / 113 7.2 Mechatronic Analysis of Urea Breath Test Systems / 117 7.2.1 Mission and Specification for a Urea Breath T