Essential Developmental Biology (häftad)
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Häftad (Paperback / softback)
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3rd Edition
John Wiley & Sons Inc
col Illustrations
col. Illustrations
274 x 218 x 18 mm
1022 g
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Essential Developmental Biology (häftad)

Essential Developmental Biology

Häftad Engelska, 2012-11-16
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Essential Developmental Biology is a comprehensive, richly illustrated introduction to all aspects of developmental biology. Written in a clear and accessible style, the third edition of this popular textbook has been expanded and updated In addition, an accompanying website - - provides instructional materials for both student and lecturer use, including animated developmental processes, a photo gallery of selected model organisms, and all artwork in downloadable format. With an emphasis throughout on the evidence underpinning the main conclusions, this book is an essential text for both introductory and more advanced courses in developmental biology. Shortlisted for the Society of Biology Book Awards 2013 in the Undergraduate Textbook category. Reviews of the Second Edition: "The second edition is a must have for anyone interested in development biology. New findings in hot fields such as stem cells, regeneration, and aging should make it attractive to a wide readership. Overall, the book is concise, well structured, and illustrated. I can highly recommend it." Peter Gruss , Max Planck Society "I have always found Jonathan Slack's writing thoughtful, provocative, and engaging, and simply fun to read. This effort is no exception. Every student of developmental biology should experience his holistic yet analytical view of the subject." Margaret Saha , College of William & Mary
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Fler böcker av Jonathan M W Slack

  • Science of Stem Cells

    Jonathan M W Slack

    Introduces all of the essential cell biology and developmental biology background for the study of stem cells  This book gives you all the important information you need to become a stem cell scientist. It covers the characterization of cells...

Övrig information

PROFESSOR JONATHAN SLACK has worked in London, Oxford and Bath and is currently Director of the Stem Cell Institute at the University of Minnesota, USA. He is a member of the European Molecular Biology Organization and a Fellow of the Academy of Medical Sciences. He has published numerous research papers on developmental biology as well as three other books, of which the most recent is Stem Cells: A Very Short Introduction.


Preface, ix About the companion website, xii Section N: Groundwork, 1 N The excitement of developmental biology, 3 Where the subject came from, 3 Impact of developmental biology, 4 Future impact, 4 Further reading, 5 O How development works, 7 Ultrashort summary, 7 Gametogenesis, 10 Early development, 12 Morphogenetic processes, 19 Growth and death, 23 Further reading, 25 P Approaches to development: developmental genetics, 27 Developmental mutants, 27 Sex chromosomes, 29 Maternal and zygotic, 29 Genetic pathways, 29 Genetic mosaics, 32 Screening for mutants, 33 Cloning of genes, 34 Gain- and loss-of-function experiments, 34 Gene duplication, 38 Limitations of developmental genetics, 39 Further reading, 40 Q Approaches to development: experimental embryology, 42 Normal development, 42 Developmental commitment, 45 Criteria for proof, 51 Further reading, 52 R Approaches to development: cell and molecular biology techniques, 54 Microscopy, 54 Study of gene expression by molecular biology methods, 58 Study of gene expression by in situ methods, 61 Microinjection, 65 Cell-labeling methods, 66 Further reading, 68 Section O: Major model organisms, 71 S Model organisms, 73 The big six, 73 Access and micromanipulation, 75 Genetics and genome maps, 75 Relevance and tempo, 76 Other organisms, 76 Further reading, 78 T Xenopus, 80 Oogenesis, maturation, and fertilization, 80 Normal development, 82 Experimental methods, 87 Processes of regional specification, 92 Inductive interactions, 95 Further reading, 104 U The zebrafish, 106 Normal development, 106 Genetics, 110 Embryological and molecular techniques, 114 Regional specification, 115 Other uses for the zebrafish, 118 Further reading, 120 V The chick, 121 Normal development, 122 Regional specifi cation of the early embryo, 127 Description of organogenesis in the chick, 133 Further reading, 140 NM The mouse, 141 Mammalian fertilization, 141 Normal development, 145 Regional specifi cation, 153 Human early development, 158 Mouse developmental genetics, 159 Other topics in mouse development, 164 Further reading, 169 NN Drosophila, 171 Insects, 171 Normal development, 173 Drosophila developmental genetics, 178 The developmental program, 181 Further reading, 197 NO Caenorhabditis elegans, 198 Adult anatomy, 198 Embryonic development, 200 Analysis of postembryonic development, 208 Further reading, 215 Section 3: Organogenesis, 217 NP Techniques for studying organogenesis and postnatal development, 219 Genetics, 219 Clonal analysis, 223 Tissue and organ culture, 226 Cell separation methods, 228 Further reading, 230 NQ Development of the nervous system, 231 Overall structure and cell types, 231 Anteroposterior patterning of the neural plate, 234 Dorsoventral patterning of the neural tube, 238 Neurogenesis and gliogenesis, 240 The neural crest, 246 Development of neuronal connectivity, 250 Further reading, 257 NR Development of mesodermal organs, 259 Somitogenesis and myogenesis, 259 The kidney, 266 Germ cell and gonadal development, 269 Limb development, 274 Blood and blood vessels, 284 The heart, 287 Further reading, 293 NS Development of endodermal organs, 296 Normal development, 296 Experimental analysis of endoderm development, 301 The pancreas, 307 Further reading, 312 NT Drosophila imaginal discs, 314 Metamorphosis, 314 Disc development, 318 Further reading, 328 Section Q: Growth, regeneration, evolution, 331 NU Tissue organization and stem cells, 333 Types of tissue, 333 Tissue renewal, 336 Stem cells, 339 Furth