Epigenetic Landscapes (inbunden)
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Format
Inbunden (Hardback)
Språk
Engelska
Antal sidor
280
Utgivningsdatum
2017-12-01
Förlag
Duke University Press
Illustrationer
21 illustrations
Dimensioner
234 x 157 x 20 mm
Vikt
499 g
Antal komponenter
1
ISBN
9780822368601

Epigenetic Landscapes

Drawings as Metaphor

av Susan Merrill Squier
Inbunden,  Engelska, 2017-12-01
1319
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Devised in the 1940s by the biologist C. H. Waddington, the epigenetic landscape is a metaphor for how gene regulation modulates cellular development. As a scientific model, it fell out of use in the late 1960s but returned at the beginning of the twenty-first century with the advent of big-data genomic research because of its utility among scientists across the life sciences to think more creatively about and to discuss genetics. In Epigenetic Landscapes Susan Merrill Squier follows the model's cultural trail, from its first visualization by the artist John Piper to its use beyond science. Squier examines three cases in which the metaphor has been imaginatively deployed to illustrate complex systems that link scientific and cultural practices: graphic medicine, landscape architecture, and bioArt. Challenging reductive understandings of epigenetics, Squier boldly reclaims the broader significance of the epigenetic landscape as a figure at the nexus of art, design, and science.
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"A largely insightful, informative and enjoyable read . . . an academic text as well as an insightful view into the remarkable melding of science and art." -- Rebecca Rahimi * Science, Medicine, and Anthropology * "Squier deserves many thanks for opening up new vistas in the history of science." -- Erik L. Peterson * Isis *

Övrig information

Susan Merrill Squier is Brill Professor Emerita of Women's, Gender, and Sexuality Studies and English at Pennsylvania State University. Her many books include Communities of the Air: Radio Century, Radio Culture and Liminal Lives: Imagining the Human at the Frontiers of Biomedicine, both also published by Duke University Press; Poultry Science, Chicken Culture: A Partial Alphabet; and, as coauthor, Graphic Medicine Manifesto.

Innehållsförteckning

Acknowledgments ix Introduction. Figuring Development beyond the Gene 1 1. The Epigenetic Landscape 21 2. A New Landscape of Thought: Behind Appearance 51 3. Embryo 69 4. The Graphic Embryo 87 5. The River in the Landscape 129 6. Designing Rivers 161 7. "A Complex System of Interactions": Art Laboratory Berlin as an Epigenetic Landscape 183 Conclusion. Anastomosis 205 Notes 215 References 241 Index 259

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