"Thoroughly updated, this second edition is the most complete reference on the methods available in the field. This edition contains comprehensive descriptions of the latest techniques, and several chapters deal with the modern analytical techniques adapted to assess and measure penetration enhancement. This volume elegantly sums up current research in the ever-broadening fields of topical penetration, enhancement and retardation. It establishes a broad framework for the topic and a foundation for continued research." In Anticancer Research, Vol. 26, 2006 "The book is an ideal and practical reference in Percutaneous Penetration Enhancersdesigned for researchers, students, biomedical and pharmaceutical scientists." International Journal of Biological Macromolecules, September 2006 "Overall, I thought the book was a very well put together review of the field of percutaneous enhancers. It will be used by both experienced academics and young researchers to bring themselves quickly up to date in their areas of interest." IFSCC Magazine, Vol. 11, No. 1, 2008
Eric Wane Smith, Howard I. Maibach
Introduction. Skin hydration and vehicle effects. Updates on chemical penetration enhancers. Updates on physical methods of penetration enhancement. Assessment of penetration enhancement. Industrial perspectives in percutaneous penetration. Regulatory perspectives in percutaneous penetration enhancement. Penetration retardation.