- Inbunden (Hardback)
- Antal sidor
- CRC Press Inc
- Ashby Jr, Charles R. / Ashby, Charles R. JR.
- 15 Tables, black and white
- 241 x 161 x 18 mm
- Antal komponenter
- 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam
- 499 g
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Bert M BalkInbunden
The Modulation of Dopaminergic Neurotransmission by Other Neurotransmitters4249
This book presents information from different scientific disciplines - behavioral, biochemical, electrophysiological, anatomical, and medical - to detail the interaction of the neurotransmitter dopamine (DA) with other neurotransmitters or neuromodulators in the brain. Internationally recognized experts discuss the interaction of DA with monoaminergic transmitters such as norepinephrine, GABA, acetylcholine, and serotonin, as well as neuropeptide neurotransmitters/neuromodulators such as neurotensin, cholecystokinin, and the opioid peptides. This is also the first book to include data from positron emission tomography (PET) studies examining the interaction of neurotransmitters in the brain.
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The Modulation Of Dopaminergic Neurotransmission By Norepinephrine, C.R. Ashby, Jr. and J.-P. Tassin Introduction The Effect of NE Agonists and Antagonists on DA Cells in the Ventral Tegmental Area (VTA) and Substantia Nigra Pars Compacta (SNC): Electrophysiological Studies The Effect of Experimental Manipulations of NE and DA Levels in the Brain Dopamine-ss-Hydroxylase Inhibitors Lesioning of NE Neurons The Effect of NE Agonists and Antagonists on DA Release from Brain Slices and on Extracellular Levels of DA as Determined Using Microdialysis The Effect of the Acute and Chronic Administration of Adrenergic Compounds on DA Utilization, Synthesis, and Turnover: Postmortem Studies The Effect of NE Agents on DA-Mediated Behaviors Amphetamine and Apomorphine-Induced Stereotypy and Locomotor Activity The Effect of NE on Basal Locomotor Activity The Effect of the Chronic Administration of NE Compounds on DA-Mediated Behaviors The Effect of the Chronic Administration of NE Compounds on DA-Mediated Behaviors The Effect of NE Neuronal Lesions on Cortical DA Effect of Cortical NE Innervation on Regulation of D1 Receptors in the Prefrontal Cortex Role of NE/DA Interactions in the "Ventral Tegmental Area" Syndrome Conclusions Acknowledgments References Dopamine-Opioid Interactions In The Basal Forebrain, L. Churchill and P.W. Kalivas Abbreviations Introduction Anatomical Evidence for a Dopamine-Opioid Interaction Cellular Organization within the Mesolimbic Circuitry Synaptic Organization within the Mesolimbic Circuitry Anatomical Modifications in Enkephalinergic Terminals or Neurons after Dopamine Depletion Biochemical Evidence for a Dopamine-Opioid Interaction Dopamine and Opioid Receptors Share Molecular Characteristics in Receptor Function and Second Messengers Opioids May Regulate Dopamine Receptor Action via cAMP-Dependent Phosphorylation Dopamine May Regulate Enkephalin Levels via Gene Expression Regulators Electrophysiological Evidence for Dopamine-Opioid Interactions Behavioral Evidence for Dopamine-Opioid Interactions Interaction between Dopamine and Opioids in Locomotion Interactions between Opioids and Dopamine in Reward Dopamine-Opioid Interactions in Mesolimbic Circuitry Interdependence Effect of Mesoaccumbens Dopamine Lesions on Opioid-Induced Behaviors Dopamine-Opioid Interactions in Neuropsychiatry Conclusions References Serotonergic Modulation Of Midbrain Dopamine Systems, M.D. Kelland and L.A. Chiodo Introduction Anatomy 5-HT Containing Pathways 5-HT Receptor Subtypes in DA-Rich Areas Developmental Compensations by 5-HT Neurons Following Neonatal DA Lesions Electrophysiological Studies 5-HT Modulation of the Basal Activity of DA Neurons 5-HT Modulation of the Pharmacological and Physiological Responsiveness of DA Neurons Is Sensory Input to DA Neurons Mediated by 5-HT? The Influence of 5-HT2A and 5-HT3 Receptors: The Mesocortical DA System and Schizophrenia DA/5-HT Hypothesis of Schizophrenia Biochemical Studies Clinical Studies MDMA: Dual Role for DA and 5-HT Biochemical and Behavioral Studies Electrophysiological Studies Further Evidence for Interactions between 5-HT and DA 5-HT Modulation of DA Release 5-HT Influence on DA-Mediated Behavior 5-HT, Cocaine, and Other Drugs of Abuse DA Influence on 5-HT Systems Conclusions Acknowledgments References Electrophysiological And Biochemical Interactions Between Dopamine And Cholecystokinin In The Brain, A.S. Freeman Introduction DA Neurons Containing CCK-8S CCK Receptors CCK Receptor Subtypes Selective CCK Receptor Antagonists Electrophysiological Effects of CCK Peptides and Antagonists Effects of CCK Peptides and CCK Antagonists on DA Neuronal Activity CCK Modulation of Impulse-Regulating D2 Autoreceptors Effects of CCK Peptides on Midbrain Non-DA Neurons Electrophysiological Effects of CCK-8S in the Forebrain Biochemical Interactions Between CCK and DA Effects of CCK Receptor Stimulation on DA Release in the Nucleus Accumbens Effects of CCK Receptor Stimulation on