Drug Metabolism (inbunden)
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Format
Inbunden (Hardback)
Språk
Engelska
Antal sidor
180
Utgivningsdatum
2007-06-01
Förlag
CRC Press Inc
Illustratör/Fotograf
black and white 179 Illustrations 3 Tables black and white
Illustrationer
3 Tables, black and white; 179 Illustrations, black and white
Dimensioner
259 x 188 x 15 mm
Vikt
486 g
Antal komponenter
1
ISBN
9780849375958

Drug Metabolism

Chemical and Enzymatic Aspects

av Jack P Uetrecht, William Trager
Inbunden,  Engelska, 2007-06-01
2605
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In order to understand drug metabolism at its most fundamental level, pharmaceutical scientists must be able to analyze drug compound structure and predict possible metabolic pathways in order to avoid the risk of adverse reactions that lead to the withdrawal of a drug from the market. This title is a comprehensive guide for recognizing the chemical underpinnings of drug metabolism. While there are numerous resources available to medicinal chemists for understanding drug structure, and to pharmacologists for discerning drug metabolism from a biological standpoint, no resource currently exists that links the chemical and biological aspects in language accessible to both-making it challenging for both groups to fully comprehend how a drug is metabolized, as well as the potential effects of the metabolites. Drug Metabolism: Chemical and Enzymatic Aspects provides extensive material to help understand drug metabolism within a biological context, and for predicting and mitigating adverse drug reactions.
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Övrig information

Uetrecht, Jack P. | Trager, William

Innehållsförteckning

Background for Non-Chemists. Background for Chemists. Oxidation Pathways and the Enzymes That Mediate Them. Reductive Pathways. Hydolytic Pathways. Conjugation Pathways. Reactive Metabolites

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