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Köp båda 2 för 2930 kr"...written to assist the pharmaceutical scientist involved in the protein formulation and delivery processes...also...of use to students doing thesis research in these areas. Of particular value...are numerous insights into critical practical issues that impact the development of protein therapeutic products." -Pharmaceutical Research (for previous edition) "concerns very timely topicswell written and organized." -Pharmaceutical Research (for previous edition) "concise and informative...the authors have wisely chosen to illustrate their information with real-life examples and case studies." -Pharmaceutical Development and Technology (for previous edition) "the most pertinent and readable summary of the familial ataxias that has been written to datean excellent summary of all the knowledge an interested clinician in this area needs to know." -European Journal of Paediatric Neurology (for previous edition) "a 'must read'.exceptionally well written.Highly recommended." -Journal of Controlled Release (for previous edition)
Eugene J. McNally, Eugene McNally, Jayne E. Hastedt, Jayne E. Hastedt
Overview of Protein Formulation and Delivery. Proetin Delivery (General Aspects). Compare and Contrast Small Molecule and Large Molecule Formulation and Delivery. Chemical and Physical Considerations in Protein and Peptide Stability. Analytical Methods and Stability Testing of Biopharmaceuticals. The Importance of a Thorough Preformulation Study. Solution Formulation of Proteins/Peptides. Special Considerations in High Concentration Protein Formulations or Formulation for Implantable Devices. Freeze-Drying Concepts: The Basics. Rational Choice of Excipients for Use in Lyophilized Formulations. Formulation of Proteins for Pulmonary Delivery. Formulation of Proteins for Incorporation into Drug Delivery Systems. Needle Free Delivery Approaches. Single Crystal Formulation Approaches (Altus Approach). High Throughput Screening-Transform Approach. Oral Delivery-Oral Heparin. Formulation of Proteins for Delivery into Liposome Formulations. Expiration Dating and Specification Setting for Biologics