Since the discovery of endothelin, major advances have been made in understanding the molecular structure and function of the endothelin receptors. At least two subtypes of receptors, designated ETA and ETB, have been identified through biochemica...
The impact of Apoptosis, or programmed cell death, is thought to play a crucial role in the development and progression of disease. Whilst Apoptosis remains extensively studied in the context of immunology, the focus of research has greatly expand...
Robert R. Ruffolo Jr.
Introduction: Medicinal Chemistry of Angiotensin II Receptors, J. Gleason and R.R. Ruffolo, Jr. Structure-Activity Relationships of Peptide Angiotensin II Receptor Agonists and Antagonists, J. Samanen and D. Regoli Conformational Models of Angiotensin II for Nonpeptide Antagonist Design, J. Samanen, J. Hempel, R. Keenan, C. Peishoff, and J. Weinstock Structure Activity Relationships of Nonpeptide Angiotensin II Receptor Antagonists, J. Weinstock and R.M. Keenan Index