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Yuval Noah HarariHäftad
For four decades, this extraordinary textbook played a pivotal role in the way biochemistry is taught, offering exceptionally clear writing, and innovative graphics, coverage of the latest research techniques and advances, and a signature emphasis on physiological and medical relevance. Those defining features are at the heart of this new edition. Paired for the first time with SaplingPlus the most innovative digital solution for biochemistry students. Offering the best combination of resources to help students visualise material and develop successful problem-solving skills in an effort to help students master complex concepts in isolation, and draw on that mastery to make connections across concepts.
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Precise, informative Illustrations - Each figure focuses on a single concept, clearly telling the story of a mechanism, pathway or process without the distraction of excess detail Jeremy M. Berg received his B.S. and M.S. degrees in Chemistry from Stanford (where he did research with Keith Hodgson and Lubert Stryer) and his Ph.D. in Chemistry from Harvard with Richard Holm. He then completed a postdoctoral fellowship with Carl Pabo in Biophysics at Johns Hopkins University School of Medicine. John L. Tymoczko is Towsley Professor of Biology at Carleton College, where he has taught since 1976. He currently teaches Biochemistry, the Metabolic Basis of Human Disease, Oncogenes and the Molecular Biology of Cancer, and Exercise Biochemistry and co-teaches an introductory course, Energy Flow in Biological Systems. Gregory J. Gatto, Jr., received his A.B. degree in chemistry from Princeton University, where he worked with Martin F. Semmelhack and was awarded the Everett S. Wallis Prize in Organic Chemistry. Lubert Stryer is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University, where he has been on the faculty since 1976. He received his M.D. from Harvard Medical School.
Part I THE MOLECULAR DESIGN OF LIFE.- 1. Biochemistry: An Evolving Science.- 2. Protein Composition and Structure.- 3. Exploring Proteins and Proteomes.- 4. DNA, RNA, and the Flow of Genetic Information.- 5. Exploring Genes and Genomes.- 6. Exploring Evolution and Bioinformatics.- 7. Hemoglobin: Portrait of a Protein in Action.- 8. Enzymes: Basic Concepts and Kinetics.- 9. Catalytic Strategies.- 10. Regulatory Strategies.- 11. Carbohydrates.- 12. Lipids and Cell Membranes.- 13. Membrane Channels and Pumps.- 14. Signal-Transduction Pathways.- Part II TRANSDUCING AND STORING ENERGY.-. 15. Metabolism: Basic Concepts and Design.- 16. Glycolysis and Gluconeogenesis.- 17. The Citric Acid Cycle.- 18. Oxidative Phosphorylation.- 19. The Light Reactions of Photosynthesis.- 20. The Calvin Cycle and the Pentose Phosphate Pathway.- 21. Glycogen Metabolism.- 22. Fatty Acid Metabolism.- 23. Protein Turnover and Amino Acid Catabolism.- Part III SYNTHESIZING THE MOLECULES OF LIFE.- 24. The Biosynthesis of Amino Acids.- 25. Nucleotide Biosynthesis.- 26. The Biosynthesis of Membrane Lipids and Steroids.- 27. The Integration of Metabolism.- 28. Drug Development.- 29. DNA Replication, Repair, and Recombination.- 30. RNA Synthesis and Processing.- 31. Protein Synthesis.- 32. The Control of Gene Expression in Prokaryotes.- 33. The Control of Gene Expression in Eukaryotes.- Part IV RESPONDING TO ENVIRONMENTAL CHANGES.- 34. Sensory Systems.- 35. The Immune System.- 36. Molecular Motors