SuperMEN1 (häftad)
Fler böcker inom
Format
Häftad (Paperback / softback)
Språk
Engelska
Antal sidor
136
Utgivningsdatum
2012-02-25
Upplaga
2010 ed.
Förlag
Springer-Verlag New York Inc.
Medarbetare
Balogh, Katalin (ed.), Patocs, Attila (ed.)
Illustrationer
15 Tables, black and white; 24 Illustrations, black and white; 136 p. 24 illus.
Antal komponenter
1
Komponenter
1 Paperback / softback
ISBN
9781461425229

Du kanske gillar

SuperMEN1 (häftad)

SuperMEN1

Pituitary, Parathyroid and Pancreas

av Katalin Balogh, Attila Patocs
Häftad Engelska, 2012-02-25
1429
Köp
Spara som favorit
Skickas inom 10-15 vardagar.
Gratis frakt inom Sverige över 159 kr för privatpersoner.
Finns även som
Visa alla 2 format & utgåvor
The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summaryfrom clinical basics and latest follow-up guidelines to the most recent molecular findings in multiple endocrine neoplasia Type I syndrome. Articles have been assembled by acknowledged experts in their respective fields to provide current perspectives on the clinical and genetic backgroundsofthis syndrome and to review carefully the latest discoveries concerning the possible functions and interactions ofmenin, the protein encoded by the MEN1gene,including itspossible role incell cycle regulation,hematopoiesis,and bone development. The goal ofthe book is also to present the most recent findings and the broadest aspects of the role of menin in tumorigenesis of the endocrine glands involved in MEN I syndrome (pituitary, parathyroid, endocrine pancreas and adrenal). The connection between the basic experimental and clinical points of view are highlighted through a discussion on animal models, which explores the field in both an inspiring and questioning manner with a focus on areas that remain to be clarified. Our goal was to bring together clinicians and basic researchers who represent a wide range of interests in this particular field of endocrine oncology. Presentingacomprehensive and current overviewofbasic experimental and clinical findings, this book can bring us closer to understanding endocrine tumorigenesis in multiple endocrine neoplasia Type I. Katalin Balogh, MD, PhD Attita Patocs, MD, MSc, PhD v ABOUT THEEDITORS. . .
Visa hela texten

Passar bra ihop

  1. SuperMEN1
  2. +
  3. Genetics of Endocrine Diseases and Syndromes

De som köpt den här boken har ofta också köpt Genetics of Endocrine Diseases and Syndromes av Peter Igaz, Attila Patocs (inbunden).

Köp båda 2 för 3418 kr

Kundrecensioner

Har du läst boken? Sätt ditt betyg »

Fler böcker av författarna

  • TraiLLD: Training In Languages of Lesser Diffusion

    TraiLLD: Training In Languages of Lesser Diffusion

    Katalin Balogh, Heidi Salaets

    The number of foreign language speakers involved in criminal procedures has quadrupled over the last thirty years. In many of these cases, the person's native language is an LLD (Language of Lesser Diffusion): a language that has relatively few sp...

    329
    Köp
    Skickas inom vardagar.
  • Genetics of Endocrine Diseases and Syndromes

    Genetics of Endocrine Diseases and Syndromes

    Peter Igaz, Attila Patocs

    This book provides a comprehensive overview of the genetic basis underlying endocrine diseases. It covers both the molecular and clinical consequences of these genetic defects, as well as the relevance for clinical care, highlighting issues of gen...

    1989
    Köp
    Skickas inom vardagar.

Övrig information

Katalin Balogh, MD, PhD: I graduated from Semmelweis University, Budapest as a Medical Doctor in 2001 and defended my PhD thesis on the clinical and genetic aspects of multiple endocrine neoplasia Type 1 in 2007. Working as a student at the Department of Physiology, then as a physician at the 2nd Department of Medicine, Semmelweis University, Budapest, I always had the inspiration to build bridges between patients, clinicians and researchers. Being a part of connecting different fields of medicine has always been and still remains a challenge for me. My main research interest is endocrine oncology. I am a member of the Endocrine Society and an international scholarship has afforded me the opportunity to work as a research fellow in Toronto. I hope to continue to build connections between people, continents and nations. Attila Patocs MD, MSc, PhD: I completed my medical and PhD training at Semmelweis University, Budapest, Hungary in 1998 and 2005, respectively. My interest has always focused on experimental laboratory work; therefore I attended and completed a biomedical engineering training at the Budapest Technical University in 2000. Between 2005-2007 I participated in a two-year postdoctoral fellowship in Dr. Charis Eng's laboratory at the Comprehensive Cancer Center of the Ohio State University and at the Genomic Medicine Institute of the Cleveland Clinic. Back in my home country from 2008 I am head of the Central Isotope Diagnostic Laboratory at the Semmelweis University and as a research associate I am working with the Molecular Medicine Research Group of the Hungarian Academy of Sciences. My research focuses on genetic and genomic characterization of endocrine tumors, on understanding of glucocorticoid signaling and on development of new, routine and molecular biological laboratory methods for diagnosis of endocrine disorders.

Innehållsförteckning

MEN1 Clinical Background.- Genetic Background of MEN1: From Genetic Homogeneity to Functional Diversity.- Menin: The Protein Behind the MEN1 Syndrome.- Cellular Functions of Menin.- The Role of Menin in Hematopoiesis.- Role of Menin in Bone Development.- Activin, TGF-? and Menin in Pituitary Tumorigenesis.- The Role of Menin in Parathyroid Tumorigenesis.- Role of Menin in Neuroendocrine Tumorigenesis.- Adrenal Tumors in MEN1 Syndrome and the Role of Menin in Adrenal Tumorigenesis.- Functional Studies of Menin through Genetic Manipulation of the Men1 Homolog in Mice.