Antimicrobial Resistance in Bacteria from Livestock and Companion Animals

"I am honored to be asked to write a preface for the collection of articles that comprise Antimicrobial Resistance in Bacteria from Livestock and Companion Animals. The authors are all leaders in the field and have provided comprehensive summaries of their knowledge in all aspects of the use of antibiotics and development of resistance in animal health. It is regrettable that it has taken 50 years to recognize that this worldwide plague of misuse and resistance development cannot be reversed. Given recent publications, the extent of antibiotic use in commercial fish farming in Southeast Asia reminds us that there are still many hurdles to be overcome if we want to control the misuse of antibiotics in humans. Finding new antimicrobials has always been difficult, and it is to be hoped that modern molecular biology and its constant technical improvements will save the day and provide humans with reliable agents for disease treatment without the inevitability of drug resistance. Improving knowledge of the science of low-molecular-weight microbial compounds will perhaps, in time, teach us how to use antibiotics for human use. Antimicrobial discovery must continue apace such that a source of reliable agents will always be available, whether for human or animal health. This compendium of interesting and focused articles is valuable, and it promises to provide expert advice on all aspects of antimicrobial resistance and ways of controlling it. Remember that in the 1950s antibiotics were miracles, but they have become menaces! It is up to us to focus on intelligent use of small molecules as cures and to finally eliminate infectious diseases in humans." --Julian Davies, University of British Columbia, Vancouver, British Columbia, Canada

Stefan Schwarz is Prof. Dr at Department of Veterinary Medicine at the Freie Universitat, Berlin Lina Cavaco is a Veterinarian and Researcher Technical University of Denmark. Jianzhong Shen is Associate Professor with Tenure, Dept. of Drug Discovery & Development, Auburn University, Harrison School of Pharmacy, USA. Frank Moller Aarestrup is Professor, Head of Research Group at National Food Institute, Research Group for Genomic Epidemiology at Technical University, Denmark.

1. History and current use of antimicrobial drugs in veterinary medicine John F. Prescott 2. Antimicrobial Susceptibility Testing of Bacteria of Veterinary Origin; Breakpoints Jeffrey L. Watts, Michael T. Sweeney and Brian V. Lubbers 3. New and Molecular Methods for the Detection of Antimicrobial Resistance (including MALDI-TOF, NGS, DNA array) Muna F. Anjum, Ea Zankari, and Henrik Hasman 4. Mechanisms and Transmission of Bacterial Resistance to Antimicrobial Agents Engeline van Duijkeren et al. 5. Resistance to Metals Used in Agricultural Production Christopher Rensing et al. 6. Resistance to Biocides in Bacteria Jean-Yves Maillard 7. Antimicrobial Resistance among Staphylococci of Animal Origin Stefan Schwarz et al. 8. Antimicrobial Resistance in Streptococcus spp. Marisa Haenni, Agnese Lupo and Jean-Yves Madec 9. Antimicrobial Resistance in Enterococcus spp. Carmen Torres et al. 10. Antimicrobial Resistance in Rhodococcus equi Steve Giguere, Londa J. Berghaus, and Jennifer Willingham-Lane 11. Antimicrobial Resistance in Listeria spp. Laura Luque-Sastre et al. 12. Antimicrobial Resistance in Nontyphoidal Salmonella Patrick F. McDermott, Shaohua Zhao, and Heather Tate 13. Antimicrobial Resistance in Escherichia coli Laurent Poirel et al. 14. Antimicrobial Resistance in Campylobacter spp. Zhangqi Shen et al. 15. Antimicrobial Resistance in Pasteurellaceae of Veterinary Origin Geovana B. Michael, Janine Bosse, and Stefan Schwarz 16. Antimicrobial Resistance in Bordetella bronchiseptica Kristina Kadlec, and Stefan Schwarz 17. Antimicrobial Resistance in Pseudomonas spp. and Acinetobacter spp. Agnese Lupo, Marisa Haenni, and Jean-Yves Madec 18. Antimicrobial Resistance in Corynebacterium spp., Arcanobacterium spp., and Trueperella pyogenes Andrea T. Fessler and Stefan Schwarz 19. Antimicrobial Resistance in Stenotrophomonas spp. Yang Wang et al. 20. Antimicrobial Resistance in Mycoplasma spp. Anne V. Gautier-Bouchardon 21. Antimicrobial Resistance in Clostridium spp., Brachyspira spp., and other Anaerobes Marie Archambault and Joseph Rubin 22. Antimicrobial Resistance in Leptospira, Brucella and Other Rarely Investigated Veterinary and Zoonotic Pathogens Darren J. Trott, Sam Abraham, and Ben Adler 23. Antimicrobial Resistance in Chlamydiales, Rickettsia, Coxiella, and Other Intracellular Pathogens Daisy Vanrompay et al. 24. Antimicrobial Drug Resistance in Fish Pathogens Ron A. Miller and Heather Harbottle 25. Antimicrobial Resistance in One-Health Perspective Scott A. McEwen and Peter J. Colignon 26. Licensing and Approval of Antimicrobial Agents for Use in Animals Constanca Pomba et al. 27. Monitoring Antimicrobial Drug Usage in Animals: Methods and Applications Nicole Werner, Scott A. McEwen, and Lothar Kreienbrock 28. The Present and Future Surveillance of Antimicrobial Resistance in Animals: Principles and Practices Shabbir Simjee et al. 29. Source Attribution Models and Risk Assessment Sara M. Pires, Ana SofiaDuarte, and Tine Hald 30. Optimization of Treatment to Minimize Resistance Selection Luca Guardabassi et al. 31. Antimicrobial Stewardship in Veterinary Medicine David H. Lloyd and Stephen W. Page