Animal Models of Acute Neurological Injuries II (inbunden)
Inbunden (Hardback)
Antal sidor
2012 ed.
Humana Press Inc.
Chen, Jun (ed.), Xu, Xiao-Ming (ed.), Xu, Zao C. (ed.), Zhang, John H. (ed.)
36 schwarz-weiße Tabellen 52 schwarz-weiße und 119 farbige Abbildungen
36 Tables, black and white; 125 Illustrations, color; 42 Illustrations, black and white; XVIII, 724
254 x 177 x 43 mm
1428 g
Antal komponenter
1 Hardback
Animal Models of Acute Neurological Injuries II (inbunden)

Animal Models of Acute Neurological Injuries II

Injury and Mechanistic Assessments, Volume 1

Inbunden Engelska, 2012-05-18
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The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries. Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system. Volume 1 examines general assessments in morphology, physiology, biochemistry and molecular biology, neurobehavior, and neuroimaging, as well as extensive sections on subarachnoid hemorrhage, cerebral vasospasm, and intracerebral hemorrhage. Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used. Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.
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Part I: General Morphological Assessments 1. Histopathological Assessments of Animal Models of Cerebral Ischemia Ami P. Raval and Bingren Hu 2. Assessment of Cell Death: Apoptosis, Necrosis, or In Between Tom Genetta, Ling Wei, and Shan Ping Yu 3. The Stereology and 3D Volume Analyses in Nervous Tissue Rabindra P. Singh, Li Shen, and Feng C. Zhou 4. Assessments of Reactive Astrogliosis Following CNS Injuries Candace L. Floyd Part II: General Physiological Assessments 5. Physiological Assessment in Stroke Research Casey Lee Hall, Osama Mohamad, Shan Ping Yu, and Ling Wei 6. EEG, Evoked Potential (EP), and Extracellular Single Unit Recordings In Vivo Jie Wu 7. Intracellular Recording In Vivo and Patch-Clamp Recording on Brain Slices Ping Deng and Zao C. Xu 8. Electrophysiological Evaluation of Synaptic Plasticity in Injured CNS Xiaoming Jin Part III: General Biochemical and Molecular Biological Assessments 9. Characterization of RNA Marcel P. Van der Brug, Mar Matarin, and Taura L. Barr 10. MicroRNA Expression Profiling of Rat Blood and Brain Tissues: TaqMan Real-Time PCR MicroRNA Assays Da-Zhi Liu, Bradley P. Ander, and Frank R. Sharp 11. Protein Analysis Anthony Kian-Fong Liou and Jun Chen 12. Application of Zymographic Methods to Study Matrix Enzymes Following Traumatic Brain Injury Lesley K. Harris, Raiford T. Black, Thomas M. Reeves, and Linda L. Phillips Part IV: General Neurobehavioral Assessments 13. Rodent Behavioral Assessment in the Home Cage Using the SmartCageTM System Xinmin Simon Xie, Jingxi Zhang , Bende Zou, James Xie, Jidong Fang, Nurulain T. Zaveri, and Taline V. Khroyan 14. Assessments of Cognitive Function Following Traumatic Brain Injury Wendy M. Reid and Dong Sun 15. Assessment of Cognitive and Sensorimotor Deficits Richard E. Hartman 16. Emotional and Anxiety Assessments in CNS Disorders Zaorui Zhao and Junfang Wu Part V: General Neuroimaging Assessments 17. Neuroimaging Assessment of Traumatic Brain Injury Janna L. Harris and William M. Brooks 18. Imaging of Myelin by Coherent Anti-Stokes Raman Scattering Microscopy Ji-Xin Cheng Part VI: Subarachnoid Hemorrhage 19. Grading Scales for Subarachnoid Hemorrhage Andrew Losiniecki and Mario Zuccarello 20. Acute Physiologic and Morphologic Assessment Following Subarachnoid Hemorrhage Vincent DiNapoli and Mario Zuccarello 21. Aneurysmal Subarachnoid Hemorrhage Grading in Animal Models Robert Ayer, Takashi Sugawara, and John H. Zhang 22. Physiological Assessments of Subarachnoid Hemorrhage Jens P. Dreier 23. Spreading Depolarization Clemens Reiffurth, Sergei A. Kirov, and Jens P. Dreier 24. Assessment of Neurovascular Coupling Cecilia Nicoletti, Nikolas Offenhauser, Devi Jorks, Sebastian Major, and Jens P. Dreier 25. Assessment of Global Ischemia Fatima A. Sehba and Joshua B. Bederson 26. Assessment of Microthromboembolism after Subarachnoid Hemorrhage Mervyn D.I. Vergouwen and R. Loch Macdonald 27. Intracranial Pressure Assessments Carla S. Jung and Andreas W. Unterberg 28. Assessment of Blood-Brain Barrier Breakdown Yoash Hassidim, Ofer Prager, Ilan Shelef, and Alon Friedman 29. Electrophysiology and Morris Water Maze to Assess Hippocampal Function after Experimental Subarachnoid Hemorrhage Asma Tariq and R. Loch Macdonald 30. Biochemical and Molecular Biological Assessments of Subarachnoid Hemorrhage Joseph F. Clark 31. Neurobehavioral Assessments of Subarachnoid Hemorrhage Hidenori Suzuki and John H. Zhang 32. Neuroima