Electrophysiology (inbunden)
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Format
Inbunden (Hardback)
Språk
Engelska
Antal sidor
162
Utgivningsdatum
2016-06-02
Upplaga
1st ed. 2016
Förlag
Springer International Publishing AG
Originalspråk
English
Illustratör/Fotograf
18 schwarz-weiße Tabellen 83 schwarz-weiße und 68 farbige Abbildungen Bibliographie
Illustrationer
18 Tables, black and white; 158 Illustrations, color; XIII, 162 p. 158 illus. in color.
Dimensioner
241 x 165 x 12 mm
Vikt
544 g
Antal komponenter
1
Komponenter
1 Hardback
ISBN
9783319300115
Electrophysiology (inbunden)

Electrophysiology

Basics, Modern Approaches and Applications

Inbunden Engelska, 2016-06-02
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This textbook presents a broad overview of topics concerning cellular electrophysiology - covering topics ranging from bioelectric phenomena recognized as far back as ancient Egypt to popular topics on the dangers of electrosmog. Without sacrificing scientific precision, this clear and concise work presents on the one hand the different methods and applications, on the other hand the biophysical fundamentals of ion-channel and carrier proteins. Numerous and carefully selected illustrations and diagrams supplement the text, while questions at the end of each chapter allow readers to test their understanding. Each section also includes references to relevant original literature for further reading. The book offers a valuable resource for students of biology, chemistry and physics with a special interest in biophysics.
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Övrig information

Dr. phil.nat. Jurgen RETTINGER Product Manager Multi Channel Systems MCS GmbH Aspenhaustrasse 21 72770 Reutlingen, Germany Jurgen Rettinger received his doctor degree in physics at Goethe-University in Frankfurt. in 1995. His focus as group leader at Max-Planck-Institute of Biophysics in Frankfurt was research of structure-function relationships of ligand-gated ion channels and teaching electrophysiology at Goethe-University Frankfurt, Shanghai Institutes of Biological Sciences and Fudan-University Shanghai. Since 2008 Jurgen Rettinger is working with Multi Channel Systems responsible as product manager for electrophysiology. Silvia SCHWARZ Research Scientist Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function Fudan University Guoshoujing Rd. 199 Shanghai 201203, China Silvia Schwarz finished her university education in biology and chemistry at Albert-Ludwigs-University Freiburg in 1974. Thereafter, she was educated and worked as teacher in biology and chemistry until 2008. Since then she works as research associate at Shanghai Research Center for Acupuncture and Meridians (Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan Univ.). Silvia Schwarz's main research focus is on antiviral effects of Chinese herbal drugs applying electrophysiological methods. Prof. Dr. rer.nat. Wolfgang SCHWARZ Professor for Physics Institut fur Biophysik, Goethe-Universitat Frankfurt Max-von-Laue-Str. 1, 60438 Frankfurt a.M., Germany Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function Fudan University Guoshoujing Rd. 199 Shanghai 201203, China Wolfgang Schwarz received his doctor degree in physics at University of Saarland in 1975. Thereafter, he spent two years as postdoc at University of Washington Seattle working on characteristics of ion channels. In 1981 he habilitated in physiology at University of Saarland and received a position as head of a Cell Physiology Laboratory at Max-Planck-Institute of Biophysics Frankfurt. Wolfgang Schwarz's main focus turned to structure-function and regulation of carrier transporters and teaching electrophysiology as professor for physics at Goethe-University Frankfurt, Shanghai Institutes of Biological Sciences and Fudan-University Shanghai. Since 2004 Wolfgang Schwarz is head of the Cell Electrophysiology Laboratory of Shanghai Research Center for Acupuncture and Meridian (Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan Univ.) and concurrent professor at Fudan University.

Innehållsförteckning

Chapter 11 Introduction1.1 INTRODUCTORY OVERVIEW1.2 HISTORY OF ELECTROPHYSIOLOGY Chapter 22 Basics: Theory2.1 ELECTRICAL CHARACTERISTICS OF BIOLOGICAL MEMBRANES 2.2 ION DISTRIBUTION AT BIOLOGICAL MEMBRANES 2.3 DONNAN DISTRIBUTION AND NERNST EQUATION 2.4 GOLDMAN-HODGKIN-KATZ EQUATION Chapter 3 3. Basics: Methods 3.1 RECORDING ELECTRICAL SIGNALS FROM BODY SURFACE 3.2 THE EXAMPLE (ECG) 3.3 RECORDING ELECTRICAL SIGNALS FROM TISSUE 3.4 RECORDING ELECTRICAL SIGNALS FROM SINGLE CELLS 3.5 APPLICATION OF THE VOLTAGE-CLAMP TECHNIQUE 3.6 THE PATCH-CLAMP TECHNIQUE Chapter 4 4 Automated Electrophysiology 4.1 AUTOMATED TWO-ELECTRODE VOLTAGE CLAMP 4.2 AUTOMATED PATCH CLAMP Chapter 5 5 Ion-selective Channels 5.1 GENERAL CHARACTERISTICS OF ION CHANNELS 5.2 SPECIFIC ION CHANNELS Chapter 6 6 Theory of Excitability 6.1 THE HODGKIN-HUXLEY DESCRIPTION OF EXCITATION 6.2 CONTINUOUS AND SALTATORY CONDUCTION OF ACTION POTENTIALS 6.3 GENERATION AND TRANSMISSION OF ACTION POTENTIALS 6.4 SUMMARY OF THE DIFFERENT TYPES OF POTENTIALS 6.5 ACTION POTENTIAL IN NON-NERVE CELLS Chapter 7 7 Carrier-mediated Transport 7.1 GENERAL CHARACTERISTICS OF CARRIERS 7.2 CARRIERS ARE LIKE CHANNELS WITH ALTERNATING GATES Chapter 8 8 Examples of Application of Electrophysiology 8.1 STRUCTURE-FUNCTION RELATIONSHIPS OF CARRIER PROTEINS 8.2 STRUCTURE-FUNCTION RELATIONSHIPS OF ION CHANNELS 8.3 VIRAL ION CHANNELS Appendix A1. THE GRAPH THEORY A2. INFLUENCE OF EXTERNAL ELECTRICAL AND MAGNETIC FIELDS A2.1. MAGNETOSTATIC FIELDS A3. A LABORATORY COURSE: Important Physical Units List of Symbols and Abbreviations Index