DNA and Histone Methylation as Cancer Targets (inbunden)
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Format
Inbunden (Hardback)
Språk
Engelska
Antal sidor
624
Utgivningsdatum
2017-09-12
Upplaga
1st ed. 2017
Förlag
Birkhauser Verlag AG
Medarbetare
Kaneda, Atsushi (ed.), Tsukada, Yu-ichi (ed.)
Illustratör/Fotograf
78 farbige Tabellen 8 schwarz-weiße und 78 farbige Abbildungen Bibliographie
Illustrationer
78 Tables, color; 81 Illustrations, color; 10 Illustrations, black and white; VIII, 624 p. 91 illus.
Dimensioner
234 x 156 x 35 mm
Vikt
1053 g
Antal komponenter
1
Komponenter
1 Hardback
ISBN
9783319597843
DNA and Histone Methylation as Cancer Targets (inbunden)

DNA and Histone Methylation as Cancer Targets

Inbunden Engelska, 2017-09-12
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This book will focus on DNA and histone methylation in epigenetics and describe how it is involved in the molecular mechanisms responsible for the development of cancer. Chapters will summarize the current knowledge of the molecular basis of DNA and histone methylation and explain how it is involved in cancer, describe the features of DNA and histone methylation associated with particular types of cancer, diagnostic/therapeutic applications, and future directions of DNA and histone methylation as cancer targets.
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Övrig information

Atsushi Kaneda, MD, PhD, is Professor, Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan. Yu-ichi Tsukada, PhD, is Professor, Advanced Biological Information Research Division, INAMORI Frontier Research Center, Kyushu University, Fukuoka, Fukuoka, Japan

Innehållsförteckning

DNA and histone methylation in epigenetics.- The molecular basis of DNA methylation.- The molecular basis of DNA demethylation.- DNA methylation changes in cancer.- Misregulation of DNA methylation regulators in cancer.- The molecular basis of histone methylation.- The molecular basis of histone demethylation.- Misregulation of histone methylation regulators in cancer.- Other histone modifications.- DNA methylation and dysregulation of miRNA in cancer.- Genomic imprinting syndromes and cancer.- DNA and Histone Methylation in Brain Cancer.- DNA and Histone Methylation in Gastric Cancer.- DNA and Histone Methylation in Hematopoietic malignancy.- DNA and Histone methylation in Lung cancer.- DNA and Histone Methylation in Liver Cancer.- DNA and Histone Methylation in Colon Cancer.- DNA and histone methylation in prostate cancer.- DNA and histone modifications in cancer diagnosis.- DNA and histone modifications in cancer therapy.- Future perspective of DNA and histone methylation as cancer targets.