Two Faces of Evil: Cancer and Neurodegeneration (häftad)

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Format: Inbunden (Hardback)
Språk: Engelska
Serie: Research and Perspectives in Alzheimer's Disease
Antal sidor: 166
Utgivningsdatum: 2011-04-07
Förlag: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Dimensioner: 229 x 160 x 15 mm
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ISBN: 9783642166013

Two Faces of Evil: Cancer and Neurodegeneration

Name: Two Faces of Evil: Cancer and Neurodegeneration
Price: 2267.00 SEK
Availability: InStock
Author: Thomas Curran, Yves Christen
ISBN: 9783642166013

av Thomas Curran, Yves Christen

Inbunden, Engelska, 2011-04-07

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Homeostasis involves a delicate interplay between generative and degenerative processes to maintain a stable internal environment. In biological systems, equilibrium is established and controlled through a series of negative feedback mechanisms driven by a range of signal transduction processes. Failures in these complex communication pathways result in instability leading to disease. Cancer represents a state of imbalance caused by an excess of cell proliferation. In contrast, neurodegeneration is a consequence of excessive cell loss in the nervous system. Both of these disorders exhort profound tolls on humanity and they have been subject to a great deal of research designed to ameliorate this suffering. For the most part, the topics have been viewed as distinct and rarely do opportunities arise for transdisciplinary discussions among experts in both fields. However, cancer and neurodegeneration represent yin-yang counterpoints in the regulation of cell growth, and it is reasonable to hypothesize that key regulatory events mediated by oncogenes and tumor suppressor genes in cancer may also affect neurodegenerative processes

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