Washout Rate of Tc-99m Mibi in Bone and Soft-Tissue Sarcomas (häftad)

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Medicin: allmänt

Format: Häftad (Paperback / softback)
Språk: Engelska
Antal sidor: 80
Utgivningsdatum: 2014-07-28
Förlag: LAP Lambert Academic Publishing
Illustrationer: black & white illustrations
Dimensioner: 229 x 152 x 5 mm
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Antal komponenter: 1
Komponenter: Paperback
ISBN: 9783659580505

Washout Rate of Tc-99m Mibi in Bone and Soft-Tissue Sarcomas

Name: Washout Rate of Tc-99m Mibi in Bone and Soft-Tissue Sarcomas
Price: 424.00 SEK
Availability: InStock
Author: Sohaib Muhammad
ISBN: 9783659580505

Is it a predictor of Tissue Necrosis caused by Neoadjuvant Therapy?

av Sohaib Muhammad

Häftad, Engelska, 2014-07-28

424

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Neoadjuvant therapy is employed before the primary treatment of sarcomas. It is not uncommon that it fails due to multi-drug resistance gene causing unnecessary delays in surgery. Tc-99m MIBI, a radiopharmaceutical, is taken-up in these tumours. Being substrate of P-glycoprotein (Pgp), its washout from the malignant tissue may predict the response of sarcoma to neoadjuvant therapy. This book presents the author's experience of in-vivo quantitative estimation of the washout rates of Tc-99m MIBI from nuclear medicine scans of various bone and soft-tissue sarcomas. These rates were then assessed for their ability to predict the effectiveness of neoadjuvant therapy initiated afterwards.

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