Biochemical Markers in Type 2 Diabetes (häftad)

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Medicin: allmänt

Format: Häftad (Paperback / softback)
Språk: Engelska
Antal sidor: 104
Utgivningsdatum: 2011-12-15
Förlag: LAP Lambert Academic Publishing
Illustrationer: black & white illustrations
Dimensioner: 229 x 152 x 6 mm
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Antal komponenter: 1
Komponenter: Paperback
ISBN: 9783847307211

Biochemical Markers in Type 2 Diabetes

Name: Biochemical Markers in Type 2 Diabetes
Price: 709.00 SEK
Availability: InStock
Author: Manish Mishra
ISBN: 9783847307211

An in-vivo study of endothelial dysfunction, pro-inflammatory and angiogenesis biomarkers in type 2 diabetics

av Manish Mishra

Häftad, Engelska, 2011-12-15

709

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Diabetes mellitus is emerging as a global health challenge and according to World Health Organization around 366 million people in the world will be affected from diabetes by the year 2030. Diabetes mellitus, though a primary disease of carbohydrate metabolism due to deficient/absences of insulin, has propensity towards vascular endothelial dysfunction resulting into microangiopathy & macroangiopathy and is the leading cause of the death in the world. This research work has established that the uncontrolled diabetics have higher cardiovascular risk, endothelial dysfunction markers, inflammatory and proatherogenic cytokines. Further, the oral antidiabetic drugs like thiazolidinedione can reduce the endothelial dysfunction markers and also could be lipid friendly due to its PPAR gamma activity. However they have propensity to increase angiogenesis which have beneficial impact on coronary revascularization with some reservations on proliferative retinopathy and diabetic neuropathy & nephropathy. This book reveals the complicated interaction of intercellular communication causative for increased cardiovascular complications in diabetics.

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