Floating, pulsatile, multiparticulate drug delivery system (häftad)
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Format
Häftad (Paperback / softback)
Språk
Engelska
Antal sidor
80
Utgivningsdatum
2012-05-19
Förlag
LAP Lambert Academic Publishing
Illustrationer
black & white illustrations
Dimensioner
229 x 152 x 5 mm
Vikt
127 g
Antal komponenter
1
Komponenter
Paperback
ISBN
9783848437894

Floating, pulsatile, multiparticulate drug delivery system

Development & Evaluation of Floating Pulsatile, Multiparticulate Drug Delivery System Using Aceclofenac as a Model Drug

av Virendra Dhakar
Häftad,  Engelska, 2012-05-19
709
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The present study is aimed to develop floating, pulsatile, multiparticulate drug delivery system intended for chronopharmacotherapy in arthritis. Cross-linked beads were prepared by using low methoxylated pectin, sodium alginate, low methoxylated pectin + Sodium alginate and low methoxylated pectin + deacetylated gellan by acid- base reaction during ionotropic gelation. Beads were dried in oven at 500 degree Cenntigrate for 4hr. Aceclofenac was used as a model drug for encapsulation. Drug loaded multiparticulates were subjected to various characterization and evaluation parameters like entrapment efficiency, buoyancy study, surface topography.
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