- Antal sidor
- Swedish Pharmaceutical Press
- 252 x 165 x 35 mm
- 1608 g
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Drugs of natural origin - a treatise of pharmacognosy
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During evolution, molecules have been developed for specific functions in nature. These bioactive substances have a potential as new drug candidates in drug development, but also as pharmacological tools, intermediates or templates for synthesis of drugs. This book deals with terrestrial and marine bioactive substances of plant, microbial or animal origin. The occurrence, biosynthesis, isolation, chemistry and medical use are described together with basic research strategies. An increased understanding of the medical importance of bioactive natural products has developed in society. Since the publication of the sixth edition, six years ago, considerable progress has been achieved in the study of biosynthetic pathways, mainly based on gene technology. The revolution in high-throughput sequencing technology has given an increasing access to microbial genome sequences, which opens up new possibilities in the discovery of novel bioactive natural products. This development is reflected in a substantial revision and expansion of the book, but also removal of some sections containing products remotely associated with drugs. The new book also contains description of novel drugs marketed since the publication of the previous edition, especially in the field of diabetes, cancer and infection.
Fler böcker av Lars Bohlin
Läkemedel från naturen : en integrerad del av medicinen
Lars Bohlin, Jan G Bruhn, Robert Burman
Intresset för växter och naturprodukter som läkemedel har exploderat de senaste trettio åren. Detta har skapat ett stort intresse för ämnet farmakognosi, den akademiska disciplin som ansvarar för forskning och utbildning om dessa medel. Läkemedel ...
Bioassay Methods in Natural Product Research and Drug Development
Lars Bohlin, Jan G Bruhn
Bioassay Methods in Natural Product Research and Drug Development contains the proceedings from the Phytochemical Society of Europe's very successful symposium on this topic, held August 24-27, 1997 in Uppsala, Sweden. In this volume, leading acad...