Introduction to Computational Molecular Biology (inbunden)
Format
Inbunden (Hardback)
Språk
Engelska
Antal sidor
320
Utgivningsdatum
1997-01-01
Förlag
PWS Publishing
Medarbetare
Meidanis, Joao
Illustrationer
Illustrations
Dimensioner
240 x 165 x 20 mm
Vikt
600 g
Antal komponenter
1
ISBN
9780534952624
Introduction to Computational Molecular Biology (inbunden)

Introduction to Computational Molecular Biology

Inbunden, Engelska, 1997-01-01

Slutsåld

Until now, those interested in the emerging field of computational molecular biology have used surveys and technical articles collected from many sources. Introduction to Computational Molecular Biology brings together major results in the field, in coherent and readable format. Setubal and Meidanis present a representative sample of problems in molecular biology, focusing on the algorithms that have been proposed to solve them. Readers will find background material on molecular biology, definitions of key terms, descriptions of models, and a full sample of algorithmic results. Key theoretical computer science concepts are emphasized, such as the improvement in asymtotic running time with better algorithms, the contrast between heuristics and an algorithm with guarantees, and the difficulty posed by NP-complete problems. Algorithms for sequence comparison, including the popular BLAST and FAST programs, are covered. Introduction to Computational Molecular Biology serves readers from both the mathematical and computing sciences as well as molecular biology. The authors assume a basic chemistry background and some training in college-level discrete mathematics and algorithms.
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Preface 1. Basic Concepts of Molecular Biology 2. Strings, Graphs, and Algorithms 3. Sequence Comparison and Database Search 4. Fragment Assembly of DNA 5. Physical Mapping of DNA 6. Phylogenetic Trees 7. Genome Rearrangements 8. Molecular Structure Prediction 9. Epilogue: Computing with DNA Answers to Selected Exercises / References / Index

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Innehållsförteckning

Preface
1. Basic Concepts of Molecular Biology
2. Strings, Graphs, and Algorithms
3. Sequence Comparison and Database Search
4. Fragment Assembly of DNA
5. Physical Mapping of DNA
6. Phylogenetic Trees
7. Genome Rearrangements
8. Molecular Structure Prediction
9. Epilogue: Computing with DNA
Answers to Selected Exercises / References / Index