Veterans, Prescription Opioids and Benzodiazepines, and Mortality, 2007–2019

Three Target Trial Emulations

Avand Medicine National Academies of Sciences, Engineering,Health and Medicine Division

Häftad, Engelska, 2025

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Beskrivning

Veterans are more likely than non-veterans to experience pain, trauma, and mental health challenges due to training and combat-related service. Treatment often results in the prescription of opioid and benzodiazepine medications.In 2024, the National Academies were tasked with convening a committee of experts to evaluate the effects of these medications on all-cause mortality of veterans, including suicide, regardless of whether information relating to such deaths was reported to the U.S. Centers for Disease Control and Prevention.The resulting report examines newly dispensed opioid pharmacotherapy in veterans without and with current benzodiazepine pharmacotherapy; varying levels of the initial baseline dosage and dosage escalation of dispensed opioid pharmacotherapy; and newly dispensed benzodiazepine compared to alternative non-benzodiazepine pharmacotherapy in veterans with consistent opioid pharmacotherapy.

Produktinformation

Utgivningsdatum:2025-04-11
Mått:216 x 279 x undefined mm
Format:Häftad
Språk:Engelska
Serie:Veterans Health
Antal sidor:334
Förlag:National Academies Press
ISBN:9780309731331

Utforska kategorier

Medicin: allmänt inom Medicin

Innehållsförteckning

Front MatterAbstractSummary1 Introduction2 A History of the Policy Landscape3 Setting the Stage4 The Effect of Opioid Prescription on All-Cause Mortality, Including Suicide Mortality, Among Those Without and With Current Benzodiazepine Prescription5 The Effect of Opioid Escalation on All-Cause Mortality, Including Suicide Mortality6 The Effect of Benzodiazepine Co-Prescribing on All-Cause Mortality, Including Suicide Mortality, Among Individuals on Consistent Opioid PharmacotherapyAppendix A: Committee Member and Staff BiosketchesAppendix B: Open Session Meeting AgendasAppendix C: Public Law 116-171Appendix D: Detailed Policy LandscapeAppendix E: Opioid Tapering and All-Cause Mortality, Including Suicide MortalityAppendix F: Report of Preliminary Results: Opioid Dose Reduction Trial EmulationAppendix G: Perspectives from the Department of Veterans Affairs Pain/Opioid Consortium on Research Veteran Engagement PanelAppendix H: Approach to Data Analysis and Code LibraryAppendix I: Covariate International Classification of Disease Code Table

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