Andrey Kolobov – författare

Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences.

Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies.

Examines a variety of medical disciplines targeted by mathematical modeling and computer simulation Discusses how the results of numerical simulations are used to support clinical decision-making Covers hemodynamics relating to various subject areas, including vascular surgery and oncological tumor treatments

Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences.Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies.- Examines a variety of medical disciplines targeted by mathematical modeling and computer simulation- Discusses how the results of numerical simulations are used to support clinical decision-making- Covers hemodynamics relating to various subject areas, including vascular surgery and oncological tumor treatments

Markov Decision Processes (MDPs) are widely popular in Artificial Intelligence for modeling sequential decision-making scenarios with probabilistic dynamics. They are the framework of choice when designing an intelligent agent that needs to act for long periods of time in an environment where its actions could have uncertain outcomes. MDPs are actively researched in two related subareas of AI, probabilistic planning and reinforcement learning. Probabilistic planning assumes known models for the agent's goals and domain dynamics, and focuses on determining how the agent should behave to achieve its objectives. On the other hand, reinforcement learning additionally learns these models based on the feedback the agent gets from the environment. This book provides a concise introduction to the use of MDPs for solving probabilistic planning problems, with an emphasis on the algorithmic perspective. It covers the whole spectrum of the field, from the basics to state-of-the-art optimal and approximation algorithms. We first describe the theoretical foundations of MDPs and the fundamental solution techniques for them. We then discuss modern optimal algorithms based on heuristic search and the use of structured representations. A major focus of the book is on the numerous approximation schemes for MDPs that have been developed in the AI literature. These include determinization-based approaches, sampling techniques, heuristic functions, dimensionality reduction, and hierarchical representations. Finally, we briefly introduce several extensions of the standard MDP classes that model and solve even more complex planning problems. Table of Contents: Introduction / MDPs / Fundamental Algorithms / Heuristic Search Algorithms / Symbolic Algorithms / Approximation Algorithms / Advanced Notes

Markov Decision Processes (MDPs) are widely popular in Artificial Intelligence for modeling sequential decision-making scenarios with probabilistic dynamics. They are the framework of choice when designing an intelligent agent that needs to act for long periods of time in an environment where its actions could have uncertain outcomes. MDPs are actively researched in two related subareas of AI, probabilistic planning and reinforcement learning. Probabilistic planning assumes known models for the agent''s goals and domain dynamics, and focuses on determining how the agent should behave to achieve its objectives. On the other hand, reinforcement learning additionally learns these models based on the feedback the agent gets from the environment. This book provides a concise introduction to the use of MDPs for solving probabilistic planning problems, with an emphasis on the algorithmic perspective. It covers the whole spectrum of the field, from the basics to state-of-the-art optimal and approximation algorithms. We first describe the theoretical foundations of MDPs and the fundamental solution techniques for them. We then discuss modern optimal algorithms based on heuristic search and the use of structured representations. A major focus of the book is on the numerous approximation schemes for MDPs that have been developed in the AI literature. These include determinization-based approaches, sampling techniques, heuristic functions, dimensionality reduction, and hierarchical representations. Finally, we briefly introduce several extensions of the standard MDP classes that model and solve even more complex planning problems. Table of Contents: Introduction / MDPs / Fundamental Algorithms / Heuristic Search Algorithms / Symbolic Algorithms / Approximation Algorithms / Advanced Notes

This book discusses all possible aspects of infectious perinatal pathology caused by different bacterial, viral, fungal, mycoplasma and protozoan pathogens. Brief and concise microbiological, epidemiological and clinical data, and all macro- and histopathological changes are illustrated. Issues related to perinatal pathology are compared with those in children and adults.Special attention is paid to viral, mycoplasma and chlamydia infections. Chlamydia and Mycoplasma lesions are practically unknown to pathologists dealing with human specimens. Several typical and rare examples from the authors’ practice are presented as well. The book is important for pathologists and clinicians (obstetricians, neonatologists, paediatricians).