Anthony A. Amato – författare

A full-color text on neuromuscular disorders that bridges the gap between translational science and practical application

Neuromuscular Disorders is comprehensive in scope, yet concise enough to serve as a valuable point-of-care guide for your daily practice. Grounded by numerous reference sources and enhanced by the experience of two seasoned clinicians, this text provides a pragmatic approach in the evaluation and management of neuromuscular diseases. Here, in a single-source, you will get an insightful look at both nerve and muscle conditions, ranging from motor neuron disease to neuropathies, neuromuscular junction disorders, and myopathies.

Every chapter in this edition has been rewritten, in many cases extensively, with the addition of contemporary citations. The content reflects the latest advances in the imaging, genetic, and immunological tools now at our disposal to understand and diagnose many neuromuscular disorders.

Highlights include:

Three new chapters covering the principles of immunomodulating treatment and the rehabilitation of neuromuscular diseases and other disorders that may be mistaken as neuromuscular mimicsA unique blend of evidence-based medicine with the personal experiences of veteran cliniciansConvenient coverage of nerve, and muscle and neuromuscular transmission disorders—both primary and secondary neuromuscular diseasesSpecific disease sections encompass the range of conditions likely to be encountered in clinical practice, including amyotrophic lateral sclerosis, myasthenia gravis, radiculopathies and plexopathies, mononeuropathies, various polyneuropathies, toxic myopathies, and dozens moreThe very latest diagnosis and treatment recommendations and protocols based on the most recent clinical literature and researchHundreds of figures including original art, EMGs, histopathology images, and clinical photos

The Handbook of Clinical Neurology Vol 101: Muscular Dystrophies discusses the pathogenesis and treatment prospects for muscular dystrophies. It summarizes the advances in molecular and cell biology, biochemistry, and other biological sciences, with an emphasis on their application to this group of muscle disorders and to their clinical implications.

Starting with an overview of muscular dystrophies, the book's 16 chapters discuss dystrophinopathies; sarcoglycanopathies; congenital muscular dystrophies; collagen VI-related myopathies; limb-girdle muscular dystrophy 2A; dysferlinopathies; limb-girdle muscular dystrophy 2H and the role of TRIM32; and caveolinopathies. The book also covers myofibrillar myopathies; Emery-Dreifuss muscular dystrophy; facioscapulohumeral dystrophy and scapuloperoneal syndromes; oculopharyngeal muscular dystrophy; myotonic dystrophy types 1 and 2; and distal muscular dystrophies.

This book is useful to basic investigators, as it offers an increased understanding of muscular dystrophies; and to clinicians, with its emphasis on issues that are relevant to the care, diagnosis, and management of patients with these disorders.

Valuable insights into the muscular dystrophies, including treatment, diagnosis, and care and patient management A comprehensive compilation of the combined wisdom of the most highly regarded physicians, experts, and scientists studying the muscular dystrophies An evaluation of the way advances in molecular and cell biology, biochemistry, and other biological sciences continue to advance the study of these disorders

The Handbook of Clinical Neurology Vol 101: Muscular Dystrophies discusses the pathogenesis and treatment prospects for muscular dystrophies. It summarizes the advances in molecular and cell biology, biochemistry, and other biological sciences, with an emphasis on their application to this group of muscle disorders and to their clinical implications.Starting with an overview of muscular dystrophies, the book''s 16 chapters discuss dystrophinopathies; sarcoglycanopathies; congenital muscular dystrophies; collagen VI-related myopathies; limb-girdle muscular dystrophy 2A; dysferlinopathies; limb-girdle muscular dystrophy 2H and the role of TRIM32; and caveolinopathies. The book also covers myofibrillar myopathies; Emery–Dreifuss muscular dystrophy; facioscapulohumeral dystrophy and scapuloperoneal syndromes; oculopharyngeal muscular dystrophy; myotonic dystrophy types 1 and 2; and distal muscular dystrophies.This book is useful to basic investigators, as it offers an increased understanding of muscular dystrophies; and to clinicians, with its emphasis on issues that are relevant to the care, diagnosis, and management of patients with these disorders.- Valuable insights into the muscular dystrophies, including treatment, diagnosis, and care and patient management- A comprehensive compilation of the combined wisdom of the most highly regarded physicians, experts, and scientists studying the muscular dystrophies- An evaluation of the way advances in molecular and cell biology, biochemistry, and other biological sciences continue to advance the study of these disorders

The fully illustrated, go-to text bridging the gap between concept and application has been updated with the latest on gene therapy and genetic testingLou Gehrig''s Disease, Muscular Dystrophy, and Degenerative Muscle Diseases are just some of the many neuromuscular disorders that practicing neurologists must understand inside and out, and this text—popular for its consistent message and engaging style—is the leading resource on the subject.Comprehensive in scope yet concise enough for on-the-spot reference, Amato and Russell’s Neuromuscular Disorders, Third Edition provides everything readers need to diagnose and treat neuromuscular disease. The expert author team delivers key insights into nerve and muscle conditions, including neuropathies, myopathies, and neuromuscular junction disorders.Neuromuscular disorders are a core rotation for neurology residents, and compose the largest single section of the ABPN certification exam in neurology—making this an invaluable resource for anyone studying for the test.The book includes chapters on:Testing in Neuromuscular DiseaseMuscle and Nerve HistopathologyGenetic TestingGene TherapyPrinciples of Immunomodulating TreatmentRehabilitation of Neuromuscular DiseasesAmyotrophic Lateral SclerosisHereditary Spastic ParaparesisGuillain-Barré Syndrome and Related DisordersNeuropathies Associated with InfectionsIdiopathic PolyneuropathyFocal Neuropathies of the Lower ExtremitiesMuscular DystrophiesCongenital MyopathiesMetabolic MyopathiesMitochondrial Disorders