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The definitive textbook on the chemical analysis of pharmaceutical drugs – fully revised and updated Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products and drug substances in biological fluids. A unique emphasis on pharmaceutical laboratory practices, such as sample preparation and separation techniques, provides an efficient and practical educational framework for undergraduate studies in areas such as pharmaceutical sciences, analytical chemistry and forensic analysis. Suitable for foundational courses, this essential undergraduate text introduces the common analytical methods used in quantitative and qualitative chemical analysis of pharmaceuticals.This extensively revised second edition includes a new chapter on chemical analysis of biopharmaceuticals, which includes discussions on identification, purity testing and assay of peptide and protein-based formulations. Also new to this edition are improved colour illustrations and tables, a streamlined chapter structure and text revised for increased clarity and comprehension. Introduces the fundamental concepts of pharmaceutical analytical chemistry and statisticsPresents a systematic investigation of pharmaceutical applications absent from other textbooks on the subjectExamines various analytical techniques commonly used in pharmaceutical laboratoriesProvides practice problems, up-to-date practical examples and detailed illustrationsIncludes updated content aligned with the current European and United States Pharmacopeia regulations and guidelines Covering the analytical techniques and concepts necessary for pharmaceutical analytical chemistry, Introduction to Pharmaceutical Analytical Chemistry is ideally suited for students of chemical and pharmaceutical sciences as well as analytical chemists transitioning into the field of pharmaceutical analytical chemistry.
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Primary source for learning pharmaceutical analytical chemistry, fully updated and revised to reflect current practice and Pharmacopoeia standards Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques, and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products, and drug substances in biological fluids. Extensively revised throughout to reflect the current European Pharmacopoeia (Ph.Eur) and United States Pharmacopeia (USP), this Third Edition presents updated methodologies, practical examples, and calculations to reflect current pharmaceutical laboratory practice. Revisions to the chapter structure, text, and figures have been implemented to improve clarity and comprehension. New practice problems, up-to-date practical examples, and detailed illustrations are also included throughout the text. Written by a team of experienced academics, Introduction to Pharmaceutical Analytical Chemistry explores topics including: Fundamentals of bases, acids, solubility, polarity, partition, stereochemistry, and pharmaceutical analytical chemistryMarketing authorizations, pharmaceutical manufacturing, titration, UV-Vis spectrophotometry, IR spectrophotometry, and atomic spectrometrySeparation principles in liquid chromatography, high-performance liquid chromatography, gas chromatography, electrophoretic methods, and mass spectrometrySample preparation, quality of analytical data and validation, and chemical analysis of pharmaceutical ingredients and preparationsBioanalysis chemical analysis of pharmaceuticals in biological fluids and chemical analysis of biopharmaceuticalsIntroduction to Pharmaceutical Analytical Chemistry is essential reading for chemists, biochemists, and other scientists entering the pharmaceutical industry, along with undergraduate and graduate students enrolled in pharmaceutical courses.