Cedric A. Mims – författare

Mims'' Pathogenesis of Infectious Disease is the landmark book in the field of infectious disease. The new, revised edition of this work provides a comprehensive, up-to-date description of the mechanisms of microbial infection and the pathogenesis of infectious disease. Presented in a clear, accessible style, it deals in an integrated manner with the spectrum of microorganisms, describing the factors common to all infectious diseases. Molecular biology, pathology, and immunology are brought together to explain the mechanisms for spread, immune response, and recovery.- Microbial gene sequencing- Up-to-date picture of the global burden of infectious diseases- Role of bacterial virulence factors in vivo, as contrasted with possibilities based on in vitro evidence- Latest data on combination vaccines, the promise of edible vaccines- The spread of antibiotic resistance genes among bacteria- HIV1 and HIV2; molecular biology, pathogenesis and origin- Latest data on tuberculosis - the number one infectious disease worldwide- Recent work on papillomaviruses, herpesviruses, BSE and variant CJD- Latest data on microbial evasion of immune defences- Origin and molecular biology of pandemic influenza- Significance of toxins- An update on vaccines, prions, immune evasion, microbial ligands and receptors

Infectious diseases are the leading cause of death worldwide. In The War Within Us, well-known author and infectious disease specialist Cedric Mims makes the intricacies of the immune system and infectious diseases less baffling for the general reader and answers the questions of how things work and why. The story is told in terms of the ancient conflict between the invader (the infectious disease) and the defender (the body''s immune system) and the strategies and counter-strategies used by both sides, making it a book that is both informative and interesting to read. The War Within Us is an ideal introduction to the basics of immunity and infection for general readers and students. It also serves as a quick reference book for physicians, researchers, and other health workers.- Parasite versus host- The conflict: how we defend ourselves- The microbe''s response to our defence- How microbes cause diseas- Thumbnail sketches of seven selected diseases: - The threat of new diseases