Fred Lisdat – författare

This book reviews the latest developments and applications in the field of biosensing, providing readers with an update of the earlier, successful edition, Biosensing for the 21st Century. In this book, readers will find comprehensive key information on the advances and challenges in biorecognition elements and transduction principles, including examples of new materials and new methods. Ranging from engineering chimeric enzymes to the progress in electrochemical sensing of drugs, the book discusses the latest innovations in the field and thus, provides the reader with a profound overview. In the field of biological recognition the focus will be on switchable sensors by engineering new proteins, the development of Molecular Imprinted Polymers (MIPs) for proteins or even larger biological entities, the construction of complex nucleic acid – protein structures for affinity sensing and the application of whole microbes.The book covers new trends in signal transduction which includes graphene-based field effect transistors, nanopores designed for high selectivity and sensitivity in analysis, plasmonic and nanophotonic sensing applying metal nanostructures up to new developments in microarray construction. An introduction in to the challenges in skin-interfaced systems for continuous biochemical sensing, offers a glimpse into the future of wearable technologies. Furthermore, actual areas of application of new sensing strategies such as the detection of various types of viruses and bacteria or the analysis of drugs will be highlighted.Each chapter provides a scholarly yet accessible perspective on the latest trends in biosensor technology. Given its breadth, the book has an interdisciplinary appeal and engages a wide readership, from students and researchers to practitioners in academia and industry, interested in the fields of biochemical/biomedical engineering and in biosensing methodologies and applications.

To detect, quantify, and model biologically signi?cant molecules is getting more and more important in our everyday life, in medicine, industry, and environment. When a group of enthusiasts like Frieder Scheller started more than 40 years ago to develop biosensors, they would not foresee that biosensors are nowavailableineverydrugstore,thatthehumangenomesequenceisavailable on the Internet, that DNA tests help in forensic cases, that we can track down thepathofourancestorsfromAfrica...This allis bioanalytics in practice! FriederSchellerisoneofthepioneersofthis?eld.So,wedidnothesitatefor longwhenThomasScheper,theSeriesEditor,askedustocompileamonograph th writtenbytheleadingspecialist tohonorhis65 birthday withafreshinsight into the ever expanding bioanalytical ?eld. Thanks to all contributors and thanks to the staff at Springer Verlag: Birgit Kollmar-Thoni, Ulrike Kreusel and Dr.Marion Hertel fortheir help! st Even in the 21 century biosensors will continue to play an important role in bioanalytics. By de?nition biosensors are characterized by a rather close contact of the biocomponent for recognition and the transducing element.Thus,thedevelopment ofbiosensors isahighlyinterdisziplanary ?eld.Future developments can be particularly seen in sensitivity enhancement down to the molecular level, switchability of the sensing device, miniaturization and integration into microsystems, incorporation of new transduction and ch- acterization methods and the use ofarti?cial recognition elements. This book tries to cover recent developments in order to illustrate the potential of thisrather fascinating area of science. Atthestartofthebook,youwill?ndachapteraboutthehistoryofbiosensors and Frieder Scheller's contribution. It gives you an impression what this re- less,unsel?shandcreativescientisthasdone.Tounderlinethebasicbiosensor idea we start here with a cartoonabout Frieder Scheller's work: XII Preface "Aller guten Dinge sind drei" ("'all good things are 3", as Germans believe). They all may partly characterize Frieder: Chancefavorsonlythepreparedmind.