Gordon W. Gribble – författare
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9 produkter
9 produkter
Del 91 - Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products
Naturally Occurring Organohalogen Compounds - A Comprehensive Update
Inbunden, Engelska, 2009
3 536 kr
Skickas inom 10-15 vardagar
Despite the long association of organohalogen compounds with human activities, nature is the producer of nearly 5,000 halogen-containing chemicals. Once dismissed as accidents of nature or isolation artifacts, organohalogen compounds represent an important and ever growing class of natural products, in many cases exhibiting exceptional biological activity. Since the last comprehensive review in 1996 (Vol. 68, this series), there have been discovered an additional 2,500 organochlorine, organobromine, and other organohalogen compounds. These natural organohalogens are biosynthesized by bacteria, fungi, lichen, plants, marine organisms of all types, insects, and higher animals including humans. These compounds are also formed abiogenically, as in volcanoes, forest fires, and other geothermal events.In some instances, natural organohalogens are precisely the same chemicals that man synthesizes for industrial use, and some of the quantities of these natural chemicals far exceed the quantities emitted by man.
Inbunden, Engelska, 2003
3 215 kr
Skickas inom 10-15 vardagar
This book summarizes the state-of-the-art knowledge on naturally occurring organohalogens, of which more than 3700 are documented. The chapters cover all aspects of this field, including the structural diversity and sources of organohalogens, the mechanisms for their formation and biodegradation, the clinical use of dichloroacetate, and the synthesis of the powerful anticancer chlorine-containing cryptophycin. Both biogenic and abiogenic sources of organohalogens are treated, the latter of which include volcanic emissions and abiogenic formation in soil. Halogenation in humans, fungi, and in the ocean are covered in separate chapters. Sources and biosynthesis of the relatively rare natural organofluorines are also discussed in this volume. By better understanding of the role nature plays in the area of organohalogens, we can more intelligently regulate the production, use, and disposal of man-made organohalogen compounds.
Häftad, Engelska, 2010
3 215 kr
Skickas inom 10-15 vardagar
This book summarizes the state-of-the-art knowledge on naturally occurring organohalogens, of which more than 3700 are documented. The chapters cover all aspects of this field, including the structural diversity and sources of organohalogens, the mechanisms for their formation and biodegradation, the clinical use of dichloroacetate, and the synthesis of the powerful anticancer chlorine-containing cryptophycin. Both biogenic and abiogenic sources of organohalogens are treated, the latter of which include volcanic emissions and abiogenic formation in soil. Halogenation in humans, fungi, and in the ocean are covered in separate chapters. Sources and biosynthesis of the relatively rare natural organofluorines are also discussed in this volume. By better understanding of the role nature plays in the area of organohalogens, we can more intelligently regulate the production, use, and disposal of man-made organohalogen compounds.
Del 26 - Topics in Heterocyclic Chemistry
Heterocyclic Scaffolds II:
Reactions and Applications of Indoles
Inbunden, Engelska, 2010
5 353 kr
Skickas inom 10-15 vardagar
Richard J. SundbergElectrophilic Substitution Reactions of IndolesTara L.S. KishbaughReactions of Indole with NucleophilesErin PelkeyMetalation of IndoleJie Jack Li ∙ Gordon W. GribbleMetal-Catalyzed Cross-Coupling Reactions for IndolesJeanese C. BadenockRadical Reactions of IndoleFariborz Firooznia ∙ Robert F. Kester ∙ Steven J. Berthel[2+2], [3+2] and [2+2+2] Cycloaddition Reactions of Indole DerivativesRobert F. Kester ∙ Steven J. Berthel ∙ Fariborz Firooznia[4+2] Cycloaddition Reactions of Indole DerivativesJonathon S. RusselOxindoles and Spirocyclic Variations:Strategies for C3 FunctionalizationLiangfeng FuAdvances in the Total Syntheses of ComplexIndole Natural Products
Del 26 - Topics in Heterocyclic Chemistry
Heterocyclic Scaffolds II:
Reactions and Applications of Indoles
Häftad, Engelska, 2012
5 353 kr
Skickas inom 10-15 vardagar
Richard J. SundbergElectrophilic Substitution Reactions of IndolesTara L.S. KishbaughReactions of Indole with NucleophilesErin PelkeyMetalation of IndoleJie Jack Li ∙ Gordon W. GribbleMetal-Catalyzed Cross-Coupling Reactions for IndolesJeanese C. BadenockRadical Reactions of IndoleFariborz Firooznia ∙ Robert F. Kester ∙ Steven J. Berthel[2+2], [3+2] and [2+2+2] Cycloaddition Reactions of Indole DerivativesRobert F. Kester ∙ Steven J. Berthel ∙ Fariborz Firooznia[4+2] Cycloaddition Reactions of Indole DerivativesJonathon S. RusselOxindoles and Spirocyclic Variations:Strategies for C3 FunctionalizationLiangfeng FuAdvances in the Total Syntheses of ComplexIndole Natural Products
Del 29 - Topics in Heterocyclic Chemistry
Metalation of Azoles and Related Five-Membered Ring Heterocycles
Inbunden, Engelska, 2012
3 749 kr
Skickas inom 10-15 vardagar
T. L.S. Kishbaugh: Metalation of Pyrrole.- K.-S. Yeung: Furans and Benzofurans.- P. E. Alford: Lithiation-Based and Magnesation-Based Strategies for the Functionalization of Imidazole: 2001–2010.- L. Fu: Metalation of Oxazoles and Benzoxazoles.- S. Roy • S. Roy • G. W. Gribble: Metalation of Pyrazoles and Indazoles.- J. C. Badenock: Metalation Reactions of Isoxazoles and Benzisoxazoles.- Y.-J. Wu: Thiazoles and Benzothiazoles.- C. F. Nutaitis: Isothiazoles and Benzisothiazoles.- E. R. Biehl: Recent Advances in the Synthesis of Thiophenes and Benzothiophenes.- J. M. Lopchuk: Mesoionics.- J. M. Lopchuk: Azoles with 3-4 Heteroatoms.
Del 29 - Topics in Heterocyclic Chemistry
Metalation of Azoles and Related Five-Membered Ring Heterocycles
Häftad, Engelska, 2014
3 749 kr
Skickas inom 10-15 vardagar
Kishbaugh: Metalation of Pyrrole.- K.-S. Fu: Metalation of Oxazoles and Benzoxazoles.- S. Gribble: Metalation of Pyrazoles and Indazoles.- J. Badenock: Metalation Reactions of Isoxazoles and Benzisoxazoles.- Y.-J. Biehl: Recent Advances in the Synthesis of Thiophenes and Benzothiophenes.- J. Lopchuk: Mesoionics.- J.
Del 91 - Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products
Naturally Occurring Organohalogen Compounds - A Comprehensive Update
Häftad, Engelska, 2012
3 641 kr
Skickas inom 10-15 vardagar
Despite the long association of organohalogen compounds with human activities, nature is the producer of nearly 5,000 halogen-containing chemicals. Once dismissed as accidents of nature or isolation artifacts, organohalogen compounds represent an important and ever growing class of natural products, in many cases exhibiting exceptional biological activity. Since the last comprehensive review in 1996 (Vol. 68, this series), there have been discovered an additional 2,500 organochlorine, organobromine, and other organohalogen compounds. These natural organohalogens are biosynthesized by bacteria, fungi, lichen, plants, marine organisms of all types, insects, and higher animals including humans. These compounds are also formed abiogenically, as in volcanoes, forest fires, and other geothermal events.In some instances, natural organohalogens are precisely the same chemicals that man synthesizes for industrial use, and some of the quantities of these natural chemicals far exceed the quantities emitted by man.
Inbunden, Engelska, 2016
1 813 kr
Tillfälligt slut
Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known.Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ringIndole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.