JArgen Fuchs – författare

The Encyclopedia of Medical Genomics and Proteomics offers trail-blazing studies and authoritative contributions from more than 400 specialists on molecular diagnostics, genomics, microbiology, genetics, pharmacogenetics, pathology, forensics, tissue and cell typing, and disease susceptibility. It features coverage of key methods and technologies such as predictive genetic and pharmacogenetic testing and tissue typing for transplantation. It compiles recommendations, research, spanning critical subjects such as DNA sequencing, point-of-care testing, quality management, oncology, cancer screening, and ethical issues related to genetics.

Nutritional genomics, also referred to as nutrigenomics, is considered one of the next frontiers in the post-genomic era. This book features the latest research on the role of oxidants and dietary antioxidants in the modulation of gene expression, aging, immune function, neuroprotection, and vascular heath. It covers the relationship between oxidants, antioxidants, and gene expression, as well as new molecular techniques for the study of redox-regulated signal transduction. It summarizes the molecular mechanisms of phytochemicals and trace elements, emphasizes the impact of variations in the human genotype on individual responses to nutrients, and offers a summary of the effect of lipid and water soluble antioxidants and fatty acids on gene expression in cultured cells, laboratory animals, and humans.

This volume illustrates the impact of environmental oxidants on the tissues of the eyes, lungs and skin, as well as on the immune system - highlighting common illnesses, injuries and pathologies induced by pro-oxidant environmental xenobiotics such as inflammation, immune response, signal transduction, regulation of gene expression, and carcinogenesis. It provides clinical presentations and discusses the effects of environmental oxidants on target organs.