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2 produkter
2 produkter
Häftad, Engelska, 1994
1 121 kr
Skickas inom 10-15 vardagar
Alzheimer's disease (AD), the most frequent cause of mental decline in the elderly, represents one of the major health problems facing modern society. Despite considerable progress in the clinical diagnosis, epidemiology, structural basis, biochemistry, molecular genetics and pharmacological aspects of AD, its aetiology, molecular backgrounds and treatment challenges are still poorly understood. This volume, based on the 2nd International Symposium on EBEWE Research Initiative in October 1993 in Salzburg, Austria, is conceived as a review of the current knowledge of morphology, diagnostic clinical and imaging techniques, methodological approaches of cognitive assessment, trial designs, outcome variables and possibilities of therapy of AD and other neurodegenerative disorders. The book's coverage is broad, and should be of interest to investigators, clinicians and researchers involved in the problems of AD.
Häftad, Engelska, 1996
564 kr
Skickas inom 10-15 vardagar
Dementia is an acquired disorder of higher cerebral functions and cognition. Because of increasing life expectancy dementia poses a major health and socio- economic problem. Alzheimer's disease accounts for 70-90% of mental decline in the elderly. Degenerative non-Alzheimer's dementi as are responsi- ble for 7-30%. These include a variety of disorders clinically characterised by progressive cognitive dysfunction often combined with focal neurological def- icits, e.g. Parkinson-plus syndromes, Lewy body dementia, lobar and multisys- tem atrophies, other neurodegenerative disorders, and prion diseases. Often it is difficult to distinguish these illnesses from Alzheimer's disease and vascu- lar dementia. In spite of considerable progress in molecular genetics, biochemistry, and neuropathology, the classification and pathogenesis of non-Alzheimer's dementias are still debatable. Diagnosis is frequently made only at postmor- tem. Because disease markers are not available for the majority of non- Alzheimer's dementias, consensus criteria for the identification of such diseas- es are warranted.These criteria could serve at a basis for early diagnosis and distinction from other dementing disorders.