Lester J. Layfield – författare

Each volume in this richly illustrated series, sponsored by the Papanicolaou Society of Cytopathology, provides an organ-based approach to the cytological and histological diagnosis of small tissue samples. Benign, pre-malignant and malignant entities are presented in a well-organized and standardized format, with high-resolution color photomicrographs, tables, tabulated specific morphologic criteria and appropriate ancillary testing algorithms. Example vignettes allow the reader to assimilate the diagnostic principles in a case-based format. This volume describes the cytologic, small core biopsy, immunohistochemical and molecular diagnostic features of musculoskeletal lesions. It provides the cytopathologist and histopathologist with a comprehensive survey of diagnostic approaches and diagnostic features for benign and malignant lesions. Each chapter contains a detailed summary of differential diagnostic features, supported by high-quality images and case studies. The print edition includes a CD-ROM offering all images in a downloadable format. With over 500 photomicrographs, this is an important resource for practising pathologists and residents in pathology.

This text presents comprehensive review of the recommendations of the Papanicolaou Society of Cytopathology for reporting results of respiratory cytology specimens along with advances in diagnostic, prognostic, and predictive immunohistochemical and molecular techniques which can be performed on cytology specimens.The majority of the text focuses on the standardized terminology and nomenclature for respiratory cytology as recommended by the Papanicolaou Society of Cytopathology. Each of the diagnostic categories are described in depth and formal definitions for each category are given along with cytologic criteria. Explanatory notes are given discussing limitations of the category as well as its malignancy risk and reproducibility. Management recommendations are supplied for each category. Sample reports documenting the preferred reporting format are also given. Each category is associated with a reference list establishing the evidence based nature of the categories.An in depth discussion of ancillary testing is provided, including the utilization of microbiologic culture, immunohistochemistry, and molecular techniques. Substantial emphasis is placed on molecular diagnostics necessary for optimization of personalized testing and the appropriate use of targeted therapies. The text represents a comprehensive resource for the state of the science of the cytologic diagnosis of respiratory lesions.

Cytopathology of Bone and Soft Tissue Tumors provides the practising pathologist with a single reference for describing and illustrating the cytologic features of musculoskeletal tumours. Using fine-needle aspiration (FNA), the approach of this work is encyclopedic: both common and rare lesions are depicted. The chapters on soft-tissue lesions are organized by direction of differentiation. Summaries of clinical findings are given along with the histopathologic and cytologic description. Key diagnostic points (in table form) and a discussion of the differential diagnosis complete each section. The section on skeletal lesions is organized along predominant cell type seen in smears. This approach facilitates grouping of lesions into diagnostically useful categories, allowing the pathologist faced with an unfamiliar lesion to rapidly access the portion of the text most useful for differential diagnosis. Within each chapter, the organization is similar to that within the soft tissue chapters. The introduction discusses technical concerns, limitations of the technique, and a diagnostic approach in both tabular and narrative form.Information on grading of soft tissue sarcomas completes the introduction.