May P Chan – författare
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2 produkter
2 produkter
Handbook of Direct Immunofluorescence
A Pattern-Based Approach to Skin and Mucosal Biopsies
Inbunden, Engelska, 2018
1 167 kr
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Immunofluorescence is a key diagnostic tool in dermatopathology, and essential in the diagnosis of connective tissue diseases, vasculitis and other cutaneous disorders. The need to interpret the results of immunofluorescence testing, and correlate these with histopathological results, is a key skill required not just of dermatopathologists but also, increasingly, of dermatologists who either read the slides themselves or use a pathology lab or academic referral centre.Handbook of Direct Immunofluorescence covers not only day-to-day findings but also less common patterns and rarities, and gives information on important diagnostic pitfalls. Each chapter is dedicated to a specific disease and is introduced by concise text that describes the clinical presentation and pathogenesis: then, multiple images show the range of histopathological and immunofluorescence findings associated with the disease in question.Key pointsPractical, clinically oriented coverage provides invaluable resource for dermato-, oral and general pathologists, as well as dermatologistsIncludes invaluable information on technical aspects (specimen procurement, transportation, etc) as well as guidance on interpreting histopathological and immunofluorescence findingsPattern-based approach serves as logical framework for reaching a diagnosis, as well as understanding when to order additional tests and how to recognise nonspecific findings
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The human skin, as the largest organ of the body, is home to numerous neoplastic and non-neoplastic disorders. The vast majority of non-neoplastic skin diseases are inflammatory in nature, while a small subset is non-inflammatory. This book covers 194 non-neoplastic dermatologic conditions, classified by their primary microscopic tissue reaction patterns. Our aim is to provide a concise, practical, and up-to-date review of these diseases. We offer a discussion on the clinical presentation, histopathologic features, pathogenesis, differential diagnosis, and management for each entity. One of the key attributes of this clinical atlas is the abundant collection of clinical and microscopic images used to illustrate the salient features of these disorders. In this book, we will focus on inflammatory dermatoses, which encompass a wide range of dermatologic conditions that can be challenging to diagnose due to significant overlaps in clinical and histopathologic features. Dermatopathologists are more likely to encounter unusual or ambiguous cases that are particularly difficult to classify. The interpretation of non-neoplastic skin biopsies requires not only microscopic pattern recognition but also careful integration of clinical history, laboratory data, and other ancillary findings, wherever available, to render the most appropriate diagnoses. We hope that this book will help our readers as they interpret challenging skin biopsies for non-neoplastic diagnoses.