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6 produkter
6 produkter
Inbunden, Engelska, 2015
3 300 kr
Skickas inom 10-15 vardagar
Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.
Inbunden, Engelska, 2015
4 397 kr
Skickas inom 10-15 vardagar
This comprehensive reference gathers vital biochemical, biomedical and clinical details in Toxinology, spanning biochemistry, molecular biology, anatomy and pharmacology, and discussing the potential for venom-based drugs. Volume 2 covers Clinical Toxinology.
Inbunden, Engelska, 2016
3 300 kr
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Itis by virtue of dedicated scientists that new toxins are discovered and that new insights arise, leading the way towards the investigation of their pharmacological effects, and hopefully, as a consequence, arriving at the discovery of venom components as new drug candidates.
Inbunden, Engelska, 2015
4 397 kr
Skickas inom 10-15 vardagar
It is worth remembering that envenomation due to scorpion stings is a substantialhealth hazard in Asian, Middle Eastern, African, and Latin American countries, with over one million people stung by scorpions every year, resulting in more than 3,000 deaths.
Inbunden, Engelska, 2016
3 629 kr
Skickas inom 10-15 vardagar
This volumeprovides the reader with recent advances in the fields of molecular toxinology,the biotechnological applications of venom toxins, and antivenom production.The content of the twenty chapters of Venom Genomics and Proteomicsillustrates not only the enormous progress made since the implementation ofomics technologies in the field of toxinology, but one also realizes the roadstill ahead to reach a holistic view of venomous systems. Advancement inhigh-throughput technologies in the field of venomics has resulted in theability to generate comprehensive venom profiles for many species. However,research on snake genomes is still in its infancy, although such studies areeagerly awaited to gain insights into the evolutionary history of snake venomproteins, including the mechanisms that originated venom and the regulation oftoxin expression. Fortunately, this objective is also at the reach of currentomic technologies. Therefore it would not be unrealistic to predict a brightnear future to the field of molecular toxinology.VenomGenomics and Proteomics covers research into the venom of scaled reptiles (lizards andsnakes), scorpions, spiders, ants and platypuses. Special consideration isgiven to a number of observations made in the area of snake venom and in theapplication of advanced genomics and proteomics techniques on a variety ofvenom samples. The final chapters give some insight into the potential clinicaluses of venom derivatives and into the importance and challenges faced in theproduction and quality control of antivenoms.
Inbunden, Engelska, 2016
3 300 kr
Skickas inom 10-15 vardagar
This book presents the structure of the main toxins of aquatic origin, their distribution, producing species and vectors, their mechanisms of action, the clinical aspects of envenomation in humans, their effects in laboratory or wild animals, their toxicokinetic properties, including the relevant treatment, detection methods and regulatory aspects for management. The work also presents the main species associated with the injuries, poisonings their toxins, mechanism of action and the clinical aspects of the envenomations by aquatic animals and discusses the actual measures utilized in the first aid and hospital treatments. Marine toxins such as palytoxins, brevetoxins, saxitoxin, ciguatoxins, okadaic acid, azaspiracid toxins, equinatoxins are also dealt with in this volume. These toxins can be lethal as well as having a complex and large molecular structure and display mechanisms by which they act very specifically on targets, receptors or on critical body proteins.Themarine and freshwater environments are the new frontiers of humanity, but the increase of economic and tourist activities provoke nasty encounters between aquatic animals and humans. The main victims are swimmers, professional and sportive fishermen, surfers and scuba divers as well as people working in related fields. The identification, knowledge and treatment of envenomations caused by venomous and poisonous animals are not adequate and the prevention of injuries still is not possible. Additionally, the immense potential of the pharmacologic effects of their toxins is not fully explored. Toxins of venomous aquatic animals can cause proteolysis, myotoxicity, hemotoxicity (mainly hemolysis), cytotoxicity and neurotoxicity. The neurotoxicity is generally associated with toxins of dinoflagellates and cyanobacteria, present in poisonous and/or contaminated invertebrates and fish.