Ronald G. Reifenberger - Böcker

About 40 % of current atomic force microscopy (AFM) research is performed in liquids, making liquid-based AFM a rapidly growing andimportant tool for the study of biological materials. This book focuses on the underlying principles and experimental aspects of AFM underliquid, with an easy-to-follow organization intended for new AFM scientists. The book also serves as an up-to-date review of new AFM techniques developed especially for biological samples.Aimed at physicists, materials scientists, biologists, analytical chemists, and medicinal chemists. An ideal reference book for libraries. From the contents: Part I: General Atomic Force Microscopy* AFM: Basic Concepts* Carbon Nanotube Tips in Atomic Force Microscopy with* Applications to Imaging in Liquid* Force Spectroscopy* Atomic Force Microscopy in Liquid* Fundamentals of AFM Cantilever Dynamics in Liquid* Environments* Single-Molecule Force Spectroscopy* High-Speed AFM for Observing Dynamic Processes in Liquid* Integration of AFM with Optical Microscopy Techniques Part II: Biological Applications* DNA and Protein-DNA Complexes* Single-Molecule Force Microscopy of Cellular Sensors* AFM-Based Single-Cell Force Spectroscopy* Nano-Surgical Manipulation of Living Cells with the AFM

The atomic force microscope (AFM) is a highly interdisciplinary instrument that enables measurements of samples in liquid, vacuum or air with unprecedented resolution. The intelligent use of this instrument requires knowledge from many distinct fields of study. These lecture notes aim to provide advanced undergraduates and beginning graduates in all fields of science and engineering with the required knowledge to sensibly use an AFM. Relevant background material is often reviewed in depth and summarized in a pedagogical, self-paced style to provide a fundamental understanding of the scientific principles underlying the use and operation of an AFM. Useful as a study guide to “Fundamentals of AFM”, an online video course available at https://nanohub.org/courses/AFM1/Suitable for Graduate/Undergraduate Independent Reading and Research Course in AFM (with the combination of book and online videos)