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This book presents the proceedings of the meeting on "Enzymes of Lipid Metabolism" which took place April 18-22, 1977, at the Mont Ste. Odile convent in Alsace, France. The meeting was convened and co-ehaired by P. Mandel and S. Gatt. L. Freysz was general seeretary. They were assisted by an international advisory commit- tee and a loeal organizing committee. The purpose of the meeting was to bring together scientists involved in research on a wide variety of aspeets of lipid metabo- lism and who have a direct interest in the problematies on inter- acting enzymes with lipid substrates. The aim was to emphasize the latter aspect rather than common enzymologieal aspects such as extraetion, purification, and protein strueture. The rpeoeedings included several symposia and four "round-table" discussions. There was also a presentation of posters, whieh were exhibited during the entire duration of the meeting. All partieipants who presented leetures or posters were requested to summarize their findings, whieh were ineluded in the book.Regretfully, the very fruitful discus- sions of the "round-tables" were not included, nor were those held in the informal atmosphere of the court yards of the eonvent, the hiking paths in the Vosges mountains, and the bar. For the purpose of coherence, the editors decided not to adhere to the original order of the lectures. The papers in the book are grouped ae- eording to the classes of enzymes and the types of reaction which they catalyze.
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This book presents the proceedings of the 2nd meeting on "Enzymes of Lipid Metabolism" which took place in Strasbourg in October, 1985. It is a sequel to the first conference bearing this title which took place, also in the vicinity of Strasbourg, in March, 1977. In either case the meetings were coorganized by L. Freysz of Strasbourg, France and S. Gatt of Jerusalem, Israel. The present meeting was set up as a joint NATO Advanced Research Workshop and CNRS-INSERM International Symposium. The conference was guided by two principles, namely, that science has no bounderies, neither has the study of lipid metabolism. Participants came from Europe, the USA, Israel and Japan and represented areas of research in lipid metabolism involving fatty acid s, cholesterylesters, glycero-and sphingolipids. The experimental approaches utilized purified enzymes, artificial and biological membranes, as well as a variety of cells, primary or cultured lines. A session was also devoted to modification of lipid enzymes and metabolism resulting from inherited, inborn defects such as the lipid storage diseases which are caused by genetic modification of degradative enzymes of lipid metabolism. A second type of disease stemming from a defect in a cell organnel (ie, the peroxisome) was also discussed. The eight and one and a half years which elapsed since the previous meeting, highlighted the changing emphasis of research in. lipid metabolism.