Advances in Cell Aging and Gerontology – serie
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13 produkter
Programmed Cell Death, Volume I
Cellular and Molecular Mechanisms
Av Mark P. Mattson, Steven Estus m. fl.
Inbunden, 2001
1488 kr
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Apoptosis, or programmed cell death, is an adaptive form of cell death that plays a critical role in turnover of mitotic cells and various tissues in the adult, including epithelial cells, fibroblasts and various endocrine cells. Programmed cell death also plays a major role in development in …
The Role of DNA Damage and Repair in Cell Aging
Inbunden, 2001
1226 kr
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Aging occurs at the level of individual cells, a complex interplay between intrinsic "programming" and exogenous "wear and tear", with genetically-determined cellular capacity to repair environmentally-induced DNA damage playing a central role in the rate of aging and its specific manifestations. …
Interorganellar Signaling in Age-Related Disease
Av Mark P. Mattson, Mattson m. fl.
Inbunden, 2001
1488 kr
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Collectively, the chapters in this work will provide the reader with novel insight into the inter-relationships of the function of different organelles in the sequences of events that lead to cellular dysfunction and degeneration in the aging human population. The chapters are rich in information …
Telomerase, Aging and Disease
Av Mark P. Mattson, Mattson m. fl.
Inbunden, 2001
1936 kr
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This volume of Advances in Cell Aging and Gerontology critically reviews the rapidly advancing area of telomerase research with a focus at the molecular and cellular levels. The clearly established function of telomerase is to maintain chromosome ends during successive rounds of cell division by …
Stem Cells: A Cellular Fountain of Youth
Inbunden, 2002
1065 kr
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This volume provides a timely and thorough review of the current state of understanding of a fascinating type of cell that is capable of forming many or all cells in the body. In humans and other mammals embryonic stem cells, the immediate offspring of the fertilized egg, are capable of forming any …
Mechanisms of Cardiovascular Aging
Av T. Hagen, Tory Hagen
Inbunden, 2002
2092 kr
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This volume of Advances in Cell Aging and Gerontology provides a timely review on the molecular and cellular basis of cardiovascular diseases (CVD). Age itself is the leading risk factor for cardiovascular diseases, which include loss of vasomotor function, athero- and arterio-sclerosis, …
Membrane Lipid Signaling in Aging and Age-Related Disease
Av M.P. Mattson
Inbunden, 2003
972 kr
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The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in …
Basic Biology and Clinical Impact of Immunosenescence
Av G. Pawelec
Inbunden, 2003
1639 kr
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Ageing is of perennial interest as a universal feature in all human societies. The genetic background and biochemical bases of ageing processes are currently being revealed in unprecedented detail. It is emerging that one of the main hurdles to be overcome in achieving a long and healthy lifespan …
Energy Metabolism and Lifespan Determination
Av M.P. Mattson
Inbunden, 2003
1329 kr
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Experts in the fields of energy metabolism, aging and oxidative stress provide an integrated view of how mechanisms involved in regulating energy metabolism are linked to fundamental processes of aging including cellular stress resistance and free radical production. During evolution signal …
Recent Advances in Psychology and Aging
Av Paul Costa, P. Costa m. fl.
Inbunden, 2003
1733 kr
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Recent Events in the Psychology of Aging documents the successful integration of aging into the mainstream of psychology. Leading psychologists present overviews of the key issues and research findings on mainstream topics. These include cognitive neuroscience, visual attention, learning, memory …
Protein Phosphorylation in Aging and Age-Related Disease
Inbunden, 2004
1395 kr
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It can be argued that ATP is the most important molecule in cells. Not only is ATP the key energy source for cells, but it is also the source of phosphate groups that are transferred to a variety of substrate proteins via the action of elaborate families of protein kinases. An equally elaborate …
Sleep and Aging
Inbunden, 2005
1937 kr
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Alterations in sleep are common manifestations of aging that can lead to significant health problems and contribute to behavioural problems associated with age-related neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Recent advances have revealed key cellular and molecular …
Genetic Aberrancies and Neurodegenerative Disorders
Av Geddes, Mark Paul Mattson m. fl.
Inbunden, 2000
1374 kr
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Genetic Aberrancies and Neurodegenerative Disorders presents critical reviews and emerging findings concerning the roles of genetic mutations and polymorphisms in the pathogenesis of a range of neurological disorders including Alzheimer's and Parkinson's diseases, trinucleotide repeat disorders, …