The Newborn Brain

Hugo Lagercrantz is Professor of Pediatrics at the Karolinska Institute and Clinical Consultant at the Astrid Lindgren Children's Hospital, Stockholm, Sweden. M. A. Hanson is Director of the Institute of Developmental Sciences, Director of the Developmental Origins of Health and Disease Division and the British Heart Foundation Professor of Cardiovascular Science at the University of Southampton, UK. Laura R. Ment is Professor of Pediatrics and Neurology at Yale University School of Medicine, New Haven, CT, USA. Donald M. Peebles is Professor of Obstetrics at the Department of Obstetrics and Gynaecology, University College London School of Medicine, London, UK.

'… wonderful book … The editors smoothly transition from the bench to the bedside by examining techniques the clinician can use to evaluate the state of brain development and injury … At a time when there is rapidly improving understanding of brain development and neonatal brain injury, this book should be of interest to scientists and clinicians alike.' Pediatrics Adolescent Medicine

• List of contributors; 1. Reflections on the origins of the human brain Jean-Pierre Changeux; Part I. Making of the Brain: 2. The molecular basis of central nervous system development Ola Hermanson and Urban Lendahl; Historical box 1; 3. Holoprosencephaly and microcephaly vera: perturbations of proliferations Verne S. Caviness Jr, Pradeep G. Bhide and Richard S. Nowakowski; Historical box 2; 4. Neuronal migration Sandrine Passemard, Angela M. Kaindl, Virginia Leverche, Pascal Dournaud and Pierre Gressens; 5. Synaptogenesis in the neocortex of the newborn: the ultimate frontier for individuation? Jean-Pierre Bourgeois; 6. Neurotrophic factors in brain development Thomas Ringstedt; Historical box 3; 7. Neurotransmitters and neuromodulators Eric Herlenius and Hugo Lagercrantz; Historical box 4; 8. Glial cell biology Arne Schousboe and Helle S. Waagepetersen; Part II. Sensory Systems and Behavior: 9. Development of the somatosensory system Sandra Rees, David Walker and Ernest Jennings; 10. Principles of endogenous and sensory activity-dependent brain development: the visual system Anna A. Penn and Carla J. Shatz; Historical box 5; 11. Fetal and neonatal development of the auditory system S. Allen Counter; 12. Newborn behaviour and perception Elena V. Kushnerenko and Mark H. Johnson; Part III. Radiological and Neurophysiological Investigation: 13. Imaging the infant brain Mary A. Rutherford; 14. Electroencephalography and amplitude-integrated EEG Lena Hellström-Westas and Ingemar Rosén; 15. Emergence of spontaneous and evoked EEG activity in the human brain Sampsa Vanhatalo and Kai Kaila; Part IV. Clinical Aspects: 16. Perinatal infections and brain injuries Donald Peebles; 17. Hypoxic-ischemic encephalopathy Deanna L. Taylor, Grisha Pirianov, A. David Edwards and Henrik Hagberg; 18. Clinical assessment and therapeutic interventions for hypoxic-ischemic encephalopathy in the full-term infant Andrew Whitelaw and Marianne Thoresen; 19. Clinical aspects of brain injury in the preterm infant Michael Weindling; Part V. Follow-Up: 20. Injury and recovery in the developing brain Koray Özduman and Laura R. Ment; 21. Development of motor functions in health and disease Mijna Hadders-Algra and Hans Forssberg; 22. Antenatal glucocorticoids and programming of neuroendocrine function and behavior Stephen G. Matthews and Amita Kapoor; Part VI. Consciousness: 23. On the emergence of consciousness Hugo Lagercrantz and Jean-Pierre Changeux; Index.