This title provides a state-of-the-art summary of immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies. It includes up-to-date information on the basic mechanisms of actions of the immunosuppressive drugs as well as a summary of the clinical trials data and the potential use of these drugs in clinical organ transplantation. In addition to describing the various immunosuppressive strategies, the book has three special features, including immunosuppression in xenotransplantation, gene therapy approaches, and transplantation tolerance. A group of investigators have been assembled to write the chapters. The book is intended for the transplant professional and the specialist who wants to stay abreast of the current status of immunosuppression in organ transplantation. The book should also be useful for basic scientists who work in the field of transplantation immunology.