PROSTATE CANCER - CLINICAL AND SCIENTIFIC ASPECTS: BRIDGING THE GAP

"For researchers, reading this book may change the way you view the work you do. For research sponsors, it may prove valuable to consider clinical applications before research is done rather than ex post facto. This is a must-read book." European Urology Today

• Prostate cancer - scientific and clinical aspects - bridging the gap: prostate cancer - the clinical dilemma; prostate cancer - the scientific dilemma. Epidemiology and genetics: epidemiology of prostate cancer; genetic aberrations in prostate tumours. Prostate gland - development differentiation and pathology (in relationship to malignancy): development and differentiation of the prostate gland; growth factors in prostatic development; the prostate and cancer - an introduction to normal morphology and histology for research scientists. Molecular and cell biology of prostate cancer: epithelial and mesenchymal cell lines of prostatic origin as models of prostate cancer; ion channels in prostate cancer; matrix metalloproteinases as potential targets for prostate cancer therapy; oncogenes and tumour suppressor genes in prostate cancer; emerging technologies and new strategies and prostate cancer research. New perspectives in prevention, control and clinical management of prostate cancer: prevention of prostate cancer; screening for prostate cancer; the molecular staging of prostate cancer; the care of patients with advanced hormone relapsed prostate cancer; the biology and treatment of bone metastases in prostate cancer; prostate cancer gene therapy; psychosocial support of the prostate cancer patient.