IgG4-Related Sclerosing Cholangitis

Terumi Kamisawa, MD, PhD, AGAF, is a gastroenterologist who specializes in pancreatobiliary disease. He became deputy director of Tokyo Metropolitan Komagome Hospital in 2015. Dr. Kamisawa gained a Master’s degree and PhD from Hirosaki University School of Medicine, Aomori, Japan, in 1982 and 1995, respectively. He became an executive board member of the Japan Biliary Association in 2011 and of the Japan Pancreas Society in 2012. Since 2007 he has been an associate editor of Pancreas and Journal of the Pancreas. He is an editorial board member of the Journal of Gastroenterology, the Journal of Hepatobiliary Pancreatic Sciences, and Gut and Liver.Myung-Hwan Kim, MD, PhD, is a gastroenterologist with a special interest in pancreatobiliary disease. He is a professor at University of Ulsan College of Medicine and Director of the Pancreatobiliary Center at the Asan Medical Center. He is a former president of the Korean Pancreatobiliary Association and also of the Korean Society of Gastrointestinal Endoscopy. He is now a Council member of both the International Association of Pancreatology (IAP) and the Asian Oceanic Pancreatic Association (AOPA).

• O​verview including classification of sclerosing cholangitis.- Epidemiology.- Pathophysiology.- Pathology.- Clinical features.- Serology.- Diagnostic criteria.- Imaging.- 1) US and CT.- 2) MRI with MRCP.- 3) ERCP.- 4) EUS and IDUS.- Differential diagnosis from primarysclerosing cholangitis.- Differential diagnosis from cholangiocarcinoma.- Tissue acquisition for histologic diagnosis.- Other organ involvements including autoimmune pancreatitis.- Treatment.- 1) Steroids.- 2) Immunomodulatory drugs.- 3) Rituximab.- Prognosis.- IgG4-related sclerosing cholangitis in America.- IgG4-related sclerosing cholangitis in Europe.- IgG4-related disease.