Affecting an estimated 2.5 million people worldwide, multiple sclerosis (MS) is the most common neurological cause of debilitation in young adults. Incurable, and with the precise causes still unknown, both diagnosis and management of the condition is complicated. This book summarizes the latest understanding of the causes of the disease, using accessible, bullet-point text to describe key clinical features and diagnostic criteria. Disease-modifying therapies and management of symptoms, including fatigue, tremor and cognitive changes, are covered in detail. With a chapter focusing solely on presentations in the emergency room, the importance of recognizing these neurological emergencies is emphasised, along with indications for admission in MS patients. The impact of MS on women's reproductive health and the increasing recognition of MS in pediatric patients is also explored. An up-to-date and practical approach to the accurate diagnosis and management of MS, this is an invaluable resource for both hospital and outpatient settings.

Affecting an estimated 2.5 million people worldwide, multiple sclerosis (MS) is the most common neurological cause of debilitation in young adults. Incurable, and with the precise causes still unknown, both diagnosis and management of the condition is complicated. This book summarizes the latest understanding of the causes of the disease, using accessible, bullet-point text to describe key clinical features and diagnostic criteria. Disease-modifying therapies and management of symptoms, including fatigue, tremor and cognitive changes, are covered in detail. With a chapter focusing solely on presentations in the emergency room, the importance of recognizing these neurological emergencies is emphasised, along with indications for admission in MS patients. The impact of MS on women''s reproductive health and the increasing recognition of MS in pediatric patients is also explored. An up-to-date and practical approach to the accurate diagnosis and management of MS, this is an invaluable resource for both hospital and outpatient settings.

Selected as a Doody’s Essential Title for 2025!For more than 30 years, Perez and Brady's Principles and Practice of Radiation Oncology has been the must-have standard reference for radiation oncologists and radiation oncology residents who need a comprehensive text covering both the biological and physical science aspects of this complex field as well as disease site-specific information on the integrated, multidisciplinary management of patients with cancer. The book has established itself as the discipline’s "text-of-record," belonging on the shelf of all of those working in the field. The Seventh Edition continues this tradition of excellence with extensive updates throughout, many new chapters, and more than 1,400 full-color illustrations that highlight key concepts in tumor pathogenesis, diagnosis, and targeted radiation therapy. Comprehensive coverage of the current state of knowledge of cancer biology; medical radiation physics; clinical radiation oncology; and radiation oncology economics, ethics, and public policy. Regular, twice-yearly content updates available with the digital version of the text. Ideal for radiation oncologists, radiation oncology residents, radiation biologists, medical radiation physicists, oncologists, physicists-in-training, radiation dosimetrists, and nurses and physician assistants working in radiation oncology departments. New chapters include: Proton and Carbon Ion Beam Dosimetry and Treatment Planning; Stereotactic Radiation Therapy; Re-Irradiation; Error Avoidance; Undergraduate, Graduate, and Continuing Medical Education in Radiation Oncology; and a completely rewritten chapter on the economics of radiation oncology. Designed to provide a better understanding of the natural history of cancer, the physical and technological methods of radiation application, the effects of irradiation on normal tissues, and the most judicious ways in which radiation therapy can be employed in the treatment of patients with cancer, either as a single modality or as part of a multi-modality treatment program. All references printed in the book are now streamlined for quick access to further information. Site-specific chapters include relevant background information on each tumor—including epidemiology, pathology, diagnostic work-up, prognostic factors, treatment techniques, applications of surgery, chemotherapy, immunotherapy and biological therapy, end results, and more. Increased focus on new approaches and technologies with new and updated chapters. Greater emphasis on palliative and supportive care reflects the role of radiation treatment in non-curative roles. An international group of expert chapter authors keeps you well-informed. A completely revised first chapter is designed to provide an overview of the discipline of radiation oncology. This will be particularly useful for residents beginning training and medical students beginning a radiation oncology clinical clerkship. The chapter is supplemented with multiple sidebars to augment the reader's understanding of the field. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Selected as a Doody’s Core Title for 2025!Updated with details on the newest therapies and sporting a new full-color design, this latest edition of Radiation Oncology: Management Decisions continues to offer comprehensive guidance for residents as well as radiation oncologists already in professional practice. You’ll discover the latest treatment plans for numerous cancer sites and tumor types, including the mouth and sinus, gastrointestinal areas, lungs, bones, and blood. Concise, easy-to-read material you can use in a clinical setting immediately with patients! Combines comprehensive overviews of basic concepts with the latest radiologic treatment regimens for a wide variety of tumor types and cancer sites. Now in full color! Bursting with hundreds of illustrations, figures, and images to illuminate visually important and state-of-the-art techniques. Heavily bulleted content format and to-the-point writing style makes content easy to digest and use with patients quickly. Chapters that address tumor- or site-specific treatments cover screening, assessment, staging, therapeutic developments, and other key information. Features an up-to-date list of commonly prescribed drugs—streamlined for easier reading—and coverage of the latest pain management and palliative treatments. Enhance Your eBook Reading ExperienceRead directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Image-guided 3D Conformal or Intensity Modu- by the various classifcation systems, which might lated Radiation Terapy aims to deliver high doses be hard to fnd in scans performed without contrast of radiation to the tumor, while trying to maintain medium. dose levels to healthy tissue within tolerable limits. Together with experienced radiologists for each Terefore, it is of key importance to defne the dif- anatomical region, we have developed a set of st- ferent target volumes, gross tumor volume (GTV), dards for the acquisition of planning CT images, clinical target volume (CTV), planning target vol- standardizing the parameters for scan performance ume (PTV), and organs at risk (OARs), on the basis and those concerning patient positioning and - of in-depth knowledge of the human anatomy, of mobilization. anatomicoradiological aspects, and of anatomical In the second section of the book we describe the and geometric variations during the radiation plan- role and importance of radiological imaging in ta- ning and treatment. get defnition, including lymph nodes, especially for We have prepared this guide to meet the needs image-guided radiation therapy (IGRT).

Image-guided 3D Conformal or Intensity Modu- by the various classifcation systems, which might lated Radiation Terapy aims to deliver high doses be hard to fnd in scans performed without contrast of radiation to the tumor, while trying to maintain medium. dose levels to healthy tissue within tolerable limits. Together with experienced radiologists for each Terefore, it is of key importance to defne the dif- anatomical region, we have developed a set of st- ferent target volumes, gross tumor volume (GTV), dards for the acquisition of planning CT images, clinical target volume (CTV), planning target vol- standardizing the parameters for scan performance ume (PTV), and organs at risk (OARs), on the basis and those concerning patient positioning and - of in-depth knowledge of the human anatomy, of mobilization. anatomicoradiological aspects, and of anatomical In the second section of the book we describe the and geometric variations during the radiation plan- role and importance of radiological imaging in ta- ning and treatment. get defnition, including lymph nodes, especially for We have prepared this guide to meet the needs image-guided radiation therapy (IGRT).

This well-received book, now in its fifth edition, is unique in providing a detailed examination of the technological basis of radiation therapy. Another unique feature is that the chapters are jointly written by North American and European authors. This considerably broadens the book’s contents and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first section covers basic concepts in treatment planning and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. The second discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners with the basic technological factors and approaches in radiation therapy.

This well-received book, now in its fifth edition, is unique in providing a detailed examination of the technological basis of radiation therapy. Another unique feature is that the chapters are jointly written by North American and European authors. This considerably broadens the book’s contents and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first section covers basic concepts in treatment planning and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. The second discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners with the basic technological factors and approaches in radiation therapy.

This well-received book, now in its fifth edition, is unique in providing a detailed examination of the technological basis of radiation therapy. Another unique feature is that the chapters are jointly written by North American and European authors. This considerably broadens the book’s contents and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first section covers basic concepts in treatment planning and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. The second discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners with the basic technological factors and approaches in radiation therapy.

Defining organs at risk is a crucial task for radiation oncologists when aiming to optimize the benefit of radiation therapy, with delivery of the maximum dose to the tumor volume while sparing healthy tissues. This book will prove an invaluable guide to the delineation of organs at risk of toxicity in patients undergoing radiotherapy. The first and second sections address the anatomy of organs at risk, discuss the pathophysiology of radiation-induced damage, and present dose constraints and methods for target volume delineation. The third section is devoted to the radiological anatomy of organs at risk as seen on typical radiotherapy planning CT scans, with a view to assisting the radiation oncologist to recognize and delineate these organs for each anatomical region – head and neck, mediastinum, abdomen, and pelvis. The book is intended both for young radiation oncologists still in training and for their senior colleagues wishing to reduce intra-institutional variations in practice and thereby to standardize the definition of clinical target volumes. ​

Defining organs at risk is a crucial task for radiation oncologists when aiming to optimize the benefit of radiation therapy, with delivery of the maximum dose to the tumor volume while sparing healthy tissues. This book will prove an invaluable guide to the delineation of organs at risk of toxicity in patients undergoing radiotherapy. The first and second sections address the anatomy of organs at risk, discuss the pathophysiology of radiation-induced damage, and present dose constraints and methods for target volume delineation. The third section is devoted to the radiological anatomy of organs at risk as seen on typical radiotherapy planning CT scans, with a view to assisting the radiation oncologist to recognize and delineate these organs for each anatomical region – head and neck, mediastinum, abdomen, and pelvis. The book is intended both for young radiation oncologists still in training and for their senior colleagues wishing to reduce intra-institutional variations in practice and thereby to standardize the definition of clinical target volumes. ​

Affecting an estimated 2.5 million people worldwide, multiple sclerosis (MS) is the most common neurological cause of debilitation in young adults. Incurable, and with the precise causes still unknown, both diagnosis and management of the condition is complicated. This book summarizes the latest understanding of the causes of the disease, using accessible, bullet-point text to describe key clinical features and diagnostic criteria. Disease-modifying therapies and management of symptoms, including fatigue, tremor and cognitive changes, are covered in detail. With a chapter focusing solely on presentations in the emergency room, the importance of recognizing these neurological emergencies is emphasised, along with indications for admission in MS patients. The impact of MS on women's reproductive health and the increasing recognition of MS in pediatric patients is also explored. An up-to-date and practical approach to the accurate diagnosis and management of MS, this is an invaluable resource for both hospital and outpatient settings.

Affecting an estimated 2.5 million people worldwide, multiple sclerosis (MS) is the most common neurological cause of debilitation in young adults. Incurable, and with the precise causes still unknown, both diagnosis and management of the condition is complicated. This book summarizes the latest understanding of the causes of the disease, using accessible, bullet-point text to describe key clinical features and diagnostic criteria. Disease-modifying therapies and management of symptoms, including fatigue, tremor and cognitive changes, are covered in detail. With a chapter focusing solely on presentations in the emergency room, the importance of recognizing these neurological emergencies is emphasised, along with indications for admission in MS patients. The impact of MS on women''s reproductive health and the increasing recognition of MS in pediatric patients is also explored. An up-to-date and practical approach to the accurate diagnosis and management of MS, this is an invaluable resource for both hospital and outpatient settings.

Selected as a Doody’s Essential Title for 2025!For more than 30 years, Perez and Brady's Principles and Practice of Radiation Oncology has been the must-have standard reference for radiation oncologists and radiation oncology residents who need a comprehensive text covering both the biological and physical science aspects of this complex field as well as disease site-specific information on the integrated, multidisciplinary management of patients with cancer. The book has established itself as the discipline’s "text-of-record," belonging on the shelf of all of those working in the field. The Seventh Edition continues this tradition of excellence with extensive updates throughout, many new chapters, and more than 1,400 full-color illustrations that highlight key concepts in tumor pathogenesis, diagnosis, and targeted radiation therapy. Comprehensive coverage of the current state of knowledge of cancer biology; medical radiation physics; clinical radiation oncology; and radiation oncology economics, ethics, and public policy. Regular, twice-yearly content updates available with the digital version of the text. Ideal for radiation oncologists, radiation oncology residents, radiation biologists, medical radiation physicists, oncologists, physicists-in-training, radiation dosimetrists, and nurses and physician assistants working in radiation oncology departments. New chapters include: Proton and Carbon Ion Beam Dosimetry and Treatment Planning; Stereotactic Radiation Therapy; Re-Irradiation; Error Avoidance; Undergraduate, Graduate, and Continuing Medical Education in Radiation Oncology; and a completely rewritten chapter on the economics of radiation oncology. Designed to provide a better understanding of the natural history of cancer, the physical and technological methods of radiation application, the effects of irradiation on normal tissues, and the most judicious ways in which radiation therapy can be employed in the treatment of patients with cancer, either as a single modality or as part of a multi-modality treatment program. All references printed in the book are now streamlined for quick access to further information. Site-specific chapters include relevant background information on each tumor—including epidemiology, pathology, diagnostic work-up, prognostic factors, treatment techniques, applications of surgery, chemotherapy, immunotherapy and biological therapy, end results, and more. Increased focus on new approaches and technologies with new and updated chapters. Greater emphasis on palliative and supportive care reflects the role of radiation treatment in non-curative roles. An international group of expert chapter authors keeps you well-informed. A completely revised first chapter is designed to provide an overview of the discipline of radiation oncology. This will be particularly useful for residents beginning training and medical students beginning a radiation oncology clinical clerkship. The chapter is supplemented with multiple sidebars to augment the reader's understanding of the field. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Selected as a Doody’s Core Title for 2025!Updated with details on the newest therapies and sporting a new full-color design, this latest edition of Radiation Oncology: Management Decisions continues to offer comprehensive guidance for residents as well as radiation oncologists already in professional practice. You’ll discover the latest treatment plans for numerous cancer sites and tumor types, including the mouth and sinus, gastrointestinal areas, lungs, bones, and blood. Concise, easy-to-read material you can use in a clinical setting immediately with patients! Combines comprehensive overviews of basic concepts with the latest radiologic treatment regimens for a wide variety of tumor types and cancer sites. Now in full color! Bursting with hundreds of illustrations, figures, and images to illuminate visually important and state-of-the-art techniques. Heavily bulleted content format and to-the-point writing style makes content easy to digest and use with patients quickly. Chapters that address tumor- or site-specific treatments cover screening, assessment, staging, therapeutic developments, and other key information. Features an up-to-date list of commonly prescribed drugs—streamlined for easier reading—and coverage of the latest pain management and palliative treatments. Enhance Your eBook Reading ExperienceRead directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Image-guided 3D Conformal or Intensity Modu- by the various classifcation systems, which might lated Radiation Terapy aims to deliver high doses be hard to fnd in scans performed without contrast of radiation to the tumor, while trying to maintain medium. dose levels to healthy tissue within tolerable limits. Together with experienced radiologists for each Terefore, it is of key importance to defne the dif- anatomical region, we have developed a set of st- ferent target volumes, gross tumor volume (GTV), dards for the acquisition of planning CT images, clinical target volume (CTV), planning target vol- standardizing the parameters for scan performance ume (PTV), and organs at risk (OARs), on the basis and those concerning patient positioning and - of in-depth knowledge of the human anatomy, of mobilization. anatomicoradiological aspects, and of anatomical In the second section of the book we describe the and geometric variations during the radiation plan- role and importance of radiological imaging in ta- ning and treatment. get defnition, including lymph nodes, especially for We have prepared this guide to meet the needs image-guided radiation therapy (IGRT).

Image-guided 3D Conformal or Intensity Modu- by the various classifcation systems, which might lated Radiation Terapy aims to deliver high doses be hard to fnd in scans performed without contrast of radiation to the tumor, while trying to maintain medium. dose levels to healthy tissue within tolerable limits. Together with experienced radiologists for each Terefore, it is of key importance to defne the dif- anatomical region, we have developed a set of st- ferent target volumes, gross tumor volume (GTV), dards for the acquisition of planning CT images, clinical target volume (CTV), planning target vol- standardizing the parameters for scan performance ume (PTV), and organs at risk (OARs), on the basis and those concerning patient positioning and - of in-depth knowledge of the human anatomy, of mobilization. anatomicoradiological aspects, and of anatomical In the second section of the book we describe the and geometric variations during the radiation plan- role and importance of radiological imaging in ta- ning and treatment. get defnition, including lymph nodes, especially for We have prepared this guide to meet the needs image-guided radiation therapy (IGRT).

This well-received book, now in its fifth edition, is unique in providing a detailed examination of the technological basis of radiation therapy. Another unique feature is that the chapters are jointly written by North American and European authors. This considerably broadens the book’s contents and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first section covers basic concepts in treatment planning and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. The second discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners with the basic technological factors and approaches in radiation therapy.

This well-received book, now in its fifth edition, is unique in providing a detailed examination of the technological basis of radiation therapy. Another unique feature is that the chapters are jointly written by North American and European authors. This considerably broadens the book’s contents and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first section covers basic concepts in treatment planning and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. The second discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners with the basic technological factors and approaches in radiation therapy.

This well-received book, now in its fifth edition, is unique in providing a detailed examination of the technological basis of radiation therapy. Another unique feature is that the chapters are jointly written by North American and European authors. This considerably broadens the book’s contents and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first section covers basic concepts in treatment planning and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. The second discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners with the basic technological factors and approaches in radiation therapy.

Defining organs at risk is a crucial task for radiation oncologists when aiming to optimize the benefit of radiation therapy, with delivery of the maximum dose to the tumor volume while sparing healthy tissues. This book will prove an invaluable guide to the delineation of organs at risk of toxicity in patients undergoing radiotherapy. The first and second sections address the anatomy of organs at risk, discuss the pathophysiology of radiation-induced damage, and present dose constraints and methods for target volume delineation. The third section is devoted to the radiological anatomy of organs at risk as seen on typical radiotherapy planning CT scans, with a view to assisting the radiation oncologist to recognize and delineate these organs for each anatomical region – head and neck, mediastinum, abdomen, and pelvis. The book is intended both for young radiation oncologists still in training and for their senior colleagues wishing to reduce intra-institutional variations in practice and thereby to standardize the definition of clinical target volumes. ​

Defining organs at risk is a crucial task for radiation oncologists when aiming to optimize the benefit of radiation therapy, with delivery of the maximum dose to the tumor volume while sparing healthy tissues. This book will prove an invaluable guide to the delineation of organs at risk of toxicity in patients undergoing radiotherapy. The first and second sections address the anatomy of organs at risk, discuss the pathophysiology of radiation-induced damage, and present dose constraints and methods for target volume delineation. The third section is devoted to the radiological anatomy of organs at risk as seen on typical radiotherapy planning CT scans, with a view to assisting the radiation oncologist to recognize and delineate these organs for each anatomical region – head and neck, mediastinum, abdomen, and pelvis. The book is intended both for young radiation oncologists still in training and for their senior colleagues wishing to reduce intra-institutional variations in practice and thereby to standardize the definition of clinical target volumes. ​