Domenico Genovesi – författare

Image-guided 3D Conformal or Intensity Modu- by the various classifcation systems, which might lated Radiation Terapy aims to deliver high doses be hard to fnd in scans performed without contrast of radiation to the tumor, while trying to maintain medium. dose levels to healthy tissue within tolerable limits. Together with experienced radiologists for each Terefore, it is of key importance to defne the dif- anatomical region, we have developed a set of st- ferent target volumes, gross tumor volume (GTV), dards for the acquisition of planning CT images, clinical target volume (CTV), planning target vol- standardizing the parameters for scan performance ume (PTV), and organs at risk (OARs), on the basis and those concerning patient positioning and - of in-depth knowledge of the human anatomy, of mobilization. anatomicoradiological aspects, and of anatomical In the second section of the book we describe the and geometric variations during the radiation plan- role and importance of radiological imaging in ta- ning and treatment. get defnition, including lymph nodes, especially for We have prepared this guide to meet the needs image-guided radiation therapy (IGRT).

Image-guided 3D Conformal or Intensity Modu- by the various classifcation systems, which might lated Radiation Terapy aims to deliver high doses be hard to fnd in scans performed without contrast of radiation to the tumor, while trying to maintain medium. dose levels to healthy tissue within tolerable limits. Together with experienced radiologists for each Terefore, it is of key importance to defne the dif- anatomical region, we have developed a set of st- ferent target volumes, gross tumor volume (GTV), dards for the acquisition of planning CT images, clinical target volume (CTV), planning target vol- standardizing the parameters for scan performance ume (PTV), and organs at risk (OARs), on the basis and those concerning patient positioning and - of in-depth knowledge of the human anatomy, of mobilization. anatomicoradiological aspects, and of anatomical In the second section of the book we describe the and geometric variations during the radiation plan- role and importance of radiological imaging in ta- ning and treatment. get defnition, including lymph nodes, especially for We have prepared this guide to meet the needs image-guided radiation therapy (IGRT).

Defining organs at risk is a crucial task for radiation oncologists when aiming to optimize the benefit of radiation therapy, with delivery of the maximum dose to the tumor volume while sparing healthy tissues. This book will prove an invaluable guide to the delineation of organs at risk of toxicity in patients undergoing radiotherapy. The first and second sections address the anatomy of organs at risk, discuss the pathophysiology of radiation-induced damage, and present dose constraints and methods for target volume delineation. The third section is devoted to the radiological anatomy of organs at risk as seen on typical radiotherapy planning CT scans, with a view to assisting the radiation oncologist to recognize and delineate these organs for each anatomical region – head and neck, mediastinum, abdomen, and pelvis. The book is intended both for young radiation oncologists still in training and for their senior colleagues wishing to reduce intra-institutional variations in practice and thereby to standardize the definition of clinical target volumes. ​

Defining organs at risk is a crucial task for radiation oncologists when aiming to optimize the benefit of radiation therapy, with delivery of the maximum dose to the tumor volume while sparing healthy tissues. This book will prove an invaluable guide to the delineation of organs at risk of toxicity in patients undergoing radiotherapy. The first and second sections address the anatomy of organs at risk, discuss the pathophysiology of radiation-induced damage, and present dose constraints and methods for target volume delineation. The third section is devoted to the radiological anatomy of organs at risk as seen on typical radiotherapy planning CT scans, with a view to assisting the radiation oncologist to recognize and delineate these organs for each anatomical region – head and neck, mediastinum, abdomen, and pelvis. The book is intended both for young radiation oncologists still in training and for their senior colleagues wishing to reduce intra-institutional variations in practice and thereby to standardize the definition of clinical target volumes. ​