Khalid S. Khan - Böcker

Today, scientists are expected to be more accountable and transparent than at any other time in history. Globally, the pursuit of knowledge creation enjoys a place of distinction, and the public expects to reap considerable benefits from the innovative contributions made by researchers. It is, therefore, more important than ever that ethics, transparency, and professionalism explicitly guide research integrity.Despite the clear importance of acquiring a fundamental understanding of clinical trials in the context of health research and innovation, medical training generally fails to cover clinical trial integrity in its curriculum, including it neither at the undergraduate nor at the postgraduate levels. This new book provides a curriculum to address this gap, offering best practice guidelines to improve the quality, openness, and trustworthiness of clinical trials and filling a current void in the market.Key Features: The first book on clinical trial integrity Provides clear guidance on how to ensure probity in peer review, appraisal of trials, and investigation of complaints concerning misconduct in clinical trials Trains and supports researchers globally on how to undertake trials with integrity Ensures that the increasing demand for public documentation of all aspects throughout the lifecycle of a clinical trial can be metThis book is essential reading for master and doctoral students undertaking courses in clinical trials, epidemiology, and medical statistics and an invaluable reference for medical journal editors and peer reviewers, clinicians who recruit patients into trials, pharmaceutical industry professionals, patient and public representatives who engage in clinical trials, systematic reviewers, guideline writers, and funders and regulators of clinical trials.

Today, scientists are expected to be more accountable and transparent than at any other time in history. Globally, the pursuit of knowledge creation enjoys a place of distinction, and the public expects to reap considerable benefits from the innovative contributions made by researchers. It is, therefore, more important than ever that ethics, transparency, and professionalism explicitly guide research integrity.Despite the clear importance of acquiring a fundamental understanding of clinical trials in the context of health research and innovation, medical training generally fails to cover clinical trial integrity in its curriculum, including it neither at the undergraduate nor at the postgraduate levels. This new book provides a curriculum to address this gap, offering best practice guidelines to improve the quality, openness, and trustworthiness of clinical trials and filling a current void in the market.Key Features: The first book on clinical trial integrity Provides clear guidance on how to ensure probity in peer review, appraisal of trials, and investigation of complaints concerning misconduct in clinical trials Trains and supports researchers globally on how to undertake trials with integrity Ensures that the increasing demand for public documentation of all aspects throughout the lifecycle of a clinical trial can be metThis book is essential reading for master and doctoral students undertaking courses in clinical trials, epidemiology, and medical statistics and an invaluable reference for medical journal editors and peer reviewers, clinicians who recruit patients into trials, pharmaceutical industry professionals, patient and public representatives who engage in clinical trials, systematic reviewers, guideline writers, and funders and regulators of clinical trials.

Evidence-based medicine (EBM) has emphasised that potential advances in healthcare must be tested and proven to do more good than harm before they are incorporated into medical practice. The E of EBM comes from the underpinning published research that is translated from the laboratory bench to the patients’ bedside. Despite this, however, there is little or no training in how to ensure translatability and usefulness of this fundamental ingredient in research for patient benefit.This book fills the gap by focusing on how research translation can be maximised to make EBM truly achievable. Reflecting the author’s considerable experience as both researcher and clinician, the book challenges debate that EBM as currently described is not fit for purpose, provides an analysis of why this is so and offers solutions as to what can be done to change the situation.Key Features:Provides objective analysis of why EBM is failing and what are the remediesDescribes how effective patient−researcher collaboration can be built through efforts and methods to engage citizens in the design, conduct and publication of studies Shows how responsible research publication should seek the input of lay reviewers to make the E of EBM patient-relevantDemonstrates how knowledge transfer can be underpinned by translatable, comprehensive evidence synthesesBy consolidating related themes in the translation journey, starting with citizen involvement in science all the way through to knowledge transfer, this unique book provides invaluable guidance to and will stimulate debate among masters and doctoral students undertaking courses in evidence-based medicine, health research methods, epidemiology and medical statistics and will also be of value to biomedical researchers, medical journal editors and peer reviewers, clinicians including doctors, nurses and allied professionals who recruit patients into health research, patient and public representatives who engage in health research, systematic reviewers, guideline writers, pharmaceutical industry professionals, medical journalists, medical writers, and any individual involved in evidence-based medicine.