The Developing Microbiome

Lessons from Early Life

Häftad, Engelska, 2020

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Beskrivning

The Developing Microbiome: Lessons from Early Life focuses on the establishment of the microbiome in early life, exposing it as a key mediator of diseases and health throughout the lifecycle. The content presents a comprehensive view of the status of the field and draws real-world correlations to health and disease states. It collates the significant research being done in the pediatric microbiome research space and bridges the knowledge gap showing the factors that impact health and disease states throughout the lifecycle. Finally, it offers knowledge on how the microbiome is and can be manipulated to promote change.

This is a perfect reference for both researchers and clinical scientists who are interested in the role of the infant microbiome in health and disease, as well as gastroenterologists and pediatricians looking to affect change in their patients.

Provides comprehensive coverage of the factors that influence microbiome development
Links research in pediatric patients to later life stages
Examines increasing evidence on the impact of the microbiome beyond the gut

Produktinformation

Utgivningsdatum:2020-05-23
Mått:152 x 229 x undefined mm
Vikt:390 g
Format:Häftad
Språk:Engelska
Antal sidor:240
Förlag:Elsevier Science
ISBN:9780128206027

Utforska kategorier

Biologi inom Naturvetenskap och teknik

Mer om författaren

Erika Claud, MD specializes in neonatology, providing care to critically ill infants. She has an interest in the diagnosis and treatment of preterm infants and conditions of the immature digestive tract. Dr. Claud's research focuses on the role of the intestinal microbiome in preterm infant development and neonatal necrotizing enterocolitis (NEC) as well as on intestinal epithelial biology as it relates to neonatal necrotizing enterocolitis (NEC), a life-threatening inflammatory bowel disorder of unknown cause that afflicts premature infants. Her work has been funded by grants from prominent institutions, including the March of Dimes and the National Institutes of Health (NIH). A dedicated educator and author, Dr. Claud has published several articles and abstracts in peer-reviewed journals and has written chapters in leading textbooks on pediatric gastrointestinal disease. In addition, she serves as an ad hoc reviewer for several scientific journals, such as the Journal of Pediatrics and Gastroenterology.

Recensioner i media

"The microbiome is a living, dynamic environment that develops over time. Infancy is considered the microbiome establishment window that most dramatically impacts neonatal health and long-term adult outcomes. “The Developing Microbiome: Lessons from Early Life offers a comprehensive view of the status of the pediatric microbiome research space, beginning with the debate surrounding an in utero microbiome and the environmental influences on microbiome succession of the infant and immune development. Succeeding chapters explore the microbiome's role in several specific conditions, including prematurity, intestinal bowel disease, neurodevelopment, food allergy, and obesity or malnutrition. In addition, each chapter includes a section on relevance beyond the pediatric population and the status of microbiome-based therapeutics." --Ann Allergy Asthma Immunol"This book gives a wonderful review of the research in this quickly evolving and very promising field. The writing is concise and well researched. I doubt it will be a bestseller, but it should be required reading for all pediatric and gastrointestinal residents as well as many others in clinical medicine." --Doody

Innehållsförteckning

1. Prenatal – placental microbiome2. Microbiome establishment and maturation3. Microbiome and Immune System Development4. Preterm infant microbiome5. Preterm infant microbiome and NEC6. Pediatric microbiome and IBD7. Microbiome and Neurodevelopment8. Microbiome and Autism9. Airway microbiome and asthma10. Microbiome and food allergy11. Skin microbiome12. Microbiome and pediatric Obesity/malnutrition/nutrition13. Manipulating the microbiome – Probiotics, FMT, Ecotherapeutics