Blood Substitutes and Oxygen Biotherapeutics

AvHenry Liu,Alan D. Kaye

Inbunden, Engelska, 2022

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Beskrivning

This book functions as a comprehensive and authoritative reference book in blood transfusion and blood substitutes.

Produktinformation

Utgivningsdatum:2022-08-09
Mått:210 x 279 x 29 mm
Vikt:1 522 g
Format:Inbunden
Språk:Engelska
Antal sidor:448
Förlag:Springer Nature Switzerland AG
ISBN:9783030959746

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Mer om författaren

Henry Liu M.DPennsylvania State University College of MedicineMilton S. Hershey Medical CenterAnesthesiology & Perioperative MedicineHershey, Pennsylvania 17033USA Dr. Alan David Kaye, MD, PhD, DABA, DABPM, DABIPP, FASAVice-Chancellor of Academic Affairs, Chief Academic Officer, and Provost, Tenured Professor of Anesthesiology and Pharmacology, Toxicology, and Neurosciences, Pain Fellowship Program Director, LSU School of Medicine, 1501 Kings Hwy, Shreveport, LA 71103 Jonathan S. JahrDavid Geffen school of Medicine at UCLALos AngelesCalifornia

Innehållsförteckning

ATP and Oxygen: the Energy Economy of the Cell.- Physiological Functions of Blood.- Hemoglobin: Physiology and Hemoglobinopathy.- The Global Burden of Anemia.- Blood Component Therapy: the History, Efficacy, and Adverse Effects in Clinical Practice.- Allogeneic Blood Transfusion: Complications and Side Effects.- The real-time effects of artificial blood substitutes on the microcirculation.- Vascular endothelium and nitric oxide.- A Brief History of Development of Nanobiotechnology-based Blood Substitutes.- Classification of Blood Substitutes.- Hemoglobin-based Oxygen Carriers.- Complications of HBOCs including clinical safety issues.- Free Hemoglobin Toxicity.- Nanotechnology-based oxygen and drug carriers.- Perfluorocarbon-based Oxygen Carriers.- Platelet Substitutes.- Plasma Substitutes.- Novel nanobiotherapeutic based blood substitutes.- Paradigm Shift.- Hemoglobin-Based Blood Substitute.- Hemoglobin vesicles as artificial red cells.- Low Volume Resuscitation Agents in Prehospital Medicine.- ErythroMer: Bio-Inspired Artificial Red Blood Cell.- OxyVita-Erythrocruorin.- HemAssist: History, clinical trials.- Development of Recombinant Hemoglobin.- Hemolink-PolyHeme.- Safety and Tolerability Study -in Stable Adult Patients with Sickle Cell disease.- Oxygent-Sanguinate.- M101, the Hemoglobin from the Sea-Hemopure: clinical trials and current status.- Perftoran: History-Oxycyte-Hemoximer.- Transplantation.- Hemorrhagic Shock: HBOCs in Trauma.- Use of Oxygen.- Regulatory Update.